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From Molecule to Men

Molecular Basis of Congenital Cardiovascular Disorders

  • Conference proceedings
  • © 2000

Overview

Editors:
  1. M. Zehender

    1. Abt. Kardiologie und Angiologie, Universität Freiburg — Med. Klinik III, Freiburg, Germany

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  2. H. Just

    1. Abt. Kardiologie und Angiologie, Universität Freiburg — Med. Klinik III, Freiburg, Germany

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  3. G. Breithardt

    1. Medizinische Klinik und Poliklinik, Innere Medizin C, Münster, Germany

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Table of contents (21 papers)

  1. Front Matter

    Pages I-X
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  2. Molecular Basis of Congenital Cardiovascular Disorders

    1. Genetics of dilated cardiomyopathy

      • L. Thierfelder
      Pages 1-6

    2. Registry of families with inherited dilated cardiomyopathy for molecular analyses

      • Wolfgang-Michael Franz, O. J. Müller, E. Grünig, M. Cremer, H. A. Katus
      Pages 7-18

    3. Distinct phenotype patterns of Ca2+ handling proteins in end-stage failing human hearts

      • Burkert Pieske, W. Schillinger, S. Dieterich, L. S. Maier, G. Hasenfuss, J. Prestle
      Pages 19-32

    4. Apoptosis in the overloaded myocardium: potential stimuli and modifying signals

      • H. Schumann, H. Heinrich, B. Bartling, D. Darmer, J. Holtz
      Pages 33-68

    5. Analysis of inherited causes of hypertrophic cardiomyopathy as part of clinical practice

      • H.-P. Vosberg, J. Moolman, C. Döhlemann, P. McKeown, S. Reith
      Pages 69-75

    6. Molecular genetics of arrhythmogenic right ventricular cardiomyopathy

      • A. Rampazzo, A. Nava, M. Miorin, N. Tiso, G. Thiene, G. A. Danieli
      Pages 77-80

    7. Cardiomyopathy: Genetics in muscular dystrophies

      • Chiara Rocco, S. Miocic, L. Mestroni
      Pages 81-84

    8. Molecular impact of ion channel mutations for the pathogenesis of long-QT (LQT) syndromes

      • Eric Schulze-Bahr, H. Wedekind, W. Haverkamp, M. Borggrefe, G. Breithardt, H. Funke
      Pages 85-98

    9. Acquired abnormal QT prolongation and torsade de pointes — clinical significance of genetic information from congenital long QT syndrome

      • Wilhelm Haverkamp, G. Mönnig, L. Eckhardt, P. Kirchhof, H. Wedekind, E. Schulze-Bahr et al.
      Pages 99-111

    10. Molecular genetic approaches to human hypertension

      • Friedrich C. Luft
      Pages 113-125

    11. Renin-angiotensin system and coronary artery disease — Interaction of angiotensin II with pro-inflammatory cytokines in human stable and unstable coronary plaques

      • B. Schieffer, Helmut Drexler
      Pages 127-141

    12. Genetics of Lipoprotein(a)

      • H. G. Kraft
      Pages 143-150

    13. The molecular mechanisms of inherited hypercholesterolemia

      • Winfried März, M. S. Nauck, E. Fisher, M. M. Hoffmann, H. Wieland
      Pages 151-169

    14. Insulin resistance: A pathogenic link between cardiovascular risk factors and atherosclerosis

      • D. Müller-Wieland, J. Kotzka, B. Knebel, J. Brüning, W. Krone
      Pages 171-178

    15. Genetic control of hemostatic factors in relation to atherosclerosis

      • J. Schüttrumpf, H. H. Watzke
      Pages 179-187

    16. Increased platelet aggregability associated with platelet GPIIIa PIA2 polymorphism: the Framingham Offspring Study

      • D. Feng, K. Lindpaintner, M. G. Larson, V. S. Rao, C. J. O’Donnell, I. Lipinska et al.
      Pages 189-199

    17. Genetic aspects of chronobiologic rhythms in cardiovascular disease

      • Björn Lemmer
      Pages 201-213

    18. Is capillary sprouting enough?

      • Wolfgang Schaper, Ivo Buschmann
      Pages 215-220

    19. Angiogenesis and gene therapy

      • P. Schratzberger, Jeffrey M. Isner
      Pages 221-232
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Keywords

About this book

From molecule to man: Medical research has indeed taken this direction, and major improvements of our understanding of the pathophysiology and epidemiology of disease have been achieved. The molecular basis of the congenital cardiovascular disorders has been extended from relatively few congenital malformations into everyday illnesses such as diabetes mellitus, hyperlipoproteinaemea, and arterial hypertension. The monogenic and, more difficult, polygenic basis for a vast majority of cardiovascular disorders are being defined more precisely from year to year. This book gives an overview of what has been achieved so far and defines the current position.

Editors and Affiliations

  • Abt. Kardiologie und Angiologie, Universität Freiburg — Med. Klinik III, Freiburg, Germany

    M. Zehender, H. Just

  • Medizinische Klinik und Poliklinik, Innere Medizin C, Münster, Germany

    G. Breithardt

Bibliographic Information

  • Book Title: From Molecule to Men

  • Book Subtitle: Molecular Basis of Congenital Cardiovascular Disorders

  • Editors: M. Zehender, H. Just, G. Breithardt

  • DOI: https://doi.org/10.1007/978-3-642-57724-6

  • Publisher: Steinkopff Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2000

  • Hardcover ISBN: 978-3-7985-1168-2Published: 01 January 2000

  • Softcover ISBN: 978-3-642-63338-6Published: 30 October 2012

  • eBook ISBN: 978-3-642-57724-6Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: X, 246

  • Topics: Cardiology, Molecular Medicine

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