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  • Book
  • © 2001

Purinergic and Pyrimidinergic Signalling II

Cardiovascular, Respiratory, Immune, Metabolic and Gastrointestinal Tract Function

Editors:

  1. Maria Pia Abbracchio

    1. Institute of Pharmacological Sciences, University of Milan, Milan, Italy

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    You can also search for this editor in PubMed   Google Scholar

  2. Michael Williams

    1. Department of Molecular Pharmacology and Biological Chemistry, Northwestern University Medical School, Chicago

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • This two-part volume is an update and objective state of the art of the current knowledge in the field, with particular emphasis on the development of novel therapeutic entities that may prove useful in several diseases by targeting the purinergic/pyrimidinergic system

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 151 / 2)

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Table of contents (14 chapters)

  1. Front Matter

    Pages I-XXVIII
    PDF

  2. Cardiovascular and Renal Systems

    1. Front Matter

      Pages 1-1
      PDF

    2. P1 Receptors in the Cardiovascular System

      • R.M. Broad, Joel Linden
      Pages 3-32

    3. P1 and P2 Receptors in the Renal System

      • E.K. Jackson
      Pages 33-71

    4. P2 Receptors in the Cardiovascular System

      • A. Pelleg, G. Vassort
      Pages 73-99

    6. P1 and P2 Receptors in Platelets

      • S.M.O. Hourani
      Pages 121-139

    7. Purinergic Signalling in Gut

      • G. Burnstock
      Pages 141-238

    8. P1 Receptors in the Respiratory System

      • I. Biaggioni, I. Feoktistov
      Pages 239-279

    9. P2 Receptors in the Respiratory System

      • C. D. Wegner
      Pages 281-300

  3. Immune System

    1. Front Matter

      Pages 301-301
      PDF

    2. Role of P1 Receptors in Inflammation

      • M.C. Montesinos, B.N. Cronstein
      Pages 303-321

    3. Role of P2 Receptors in the Immune System

      • G.R. Dubyak
      Pages 323-354

    4. On the Role of the P2X7 Receptor in the Immune System

      • F.Di Virgilio, V. Vishwanath, D. Ferrari
      Pages 355-374

    5. Purinergic Receptors and the Pharmacology of Type 2 Diabetes

      • P. Petit, D. Hillaire-Buys, M.M. Loubatières-Mariani, J. Chapal
      Pages 377-391

  4. Back Matter

    Pages 435-442
    PDF
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About this book

Physiological, pharmacological and molecular biological data generated over the past three decades have demonstrated the existence of two major families of extracellular receptors, the P1, a family of four G-protein coupled receptors and the P2, a family of at least 12 receptors responsive to purine (ATP, ADP) and pyrimidine (UTP) nucleotides through which adenosine and ATP can function as extracellular messengers. The present two-part volume represents an integrated compendium of invited chapters by leading researchers in the area focusing on advances in the understanding of purinergic and pyrimidinergic signaling systems, their role(s) in tissue function and pathophysiology and advances in developing potential new medications based on the modulation of P1 and P2 receptor signaling processes. The volumes will thus provide the reader with a topical, comprehensive and integrated overview of this important area.
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Keywords

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Editors and Affiliations

  • Institute of Pharmacological Sciences, University of Milan, Milan, Italy

    Maria Pia Abbracchio

  • Department of Molecular Pharmacology and Biological Chemistry, Northwestern University Medical School, Chicago

    Michael Williams

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Bibliographic Information

  • Book Title: Purinergic and Pyrimidinergic Signalling II

  • Book Subtitle: Cardiovascular, Respiratory, Immune, Metabolic and Gastrointestinal Tract Function

  • Editors: Maria Pia Abbracchio, Michael Williams

  • Series Title: Handbook of Experimental Pharmacology

  • DOI: https://doi.org/10.1007/978-3-642-56921-0

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2001

  • Hardcover ISBN: 978-3-540-67848-9Published: 12 February 2001

  • Softcover ISBN: 978-3-642-63223-5Published: 14 October 2012

  • eBook ISBN: 978-3-642-56921-0Published: 06 December 2012

  • Series ISSN: 0171-2004

  • Series E-ISSN: 1865-0325

  • Edition Number: 1

  • Number of Pages: XXVIII, 442

  • Topics: Pharmacology/Toxicology, Human Physiology, Immunology, Endocrinology, Cell Biology, Molecular Medicine

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Access via your institution

Buy it now

eBook USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

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