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Immunostimulatory DNA Sequences

  • Book
  • © 2001

Overview

Editors:
  1. Eyal Raz

    1. Dept. of Medicine-0663, University of California, San Diego, La Jolla, USA

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Table of contents (18 chapters)

  1. Front Matter

    Pages I-VIII
    Download chapter PDF

  2. Introduction to immunostimulatory DNA sequences

    • John Van Uden, Eyal Raz
    Pages 1-9

  3. The discovery of immunostimulatory DNA sequence

    • Saburo Yamamoto, Toshiko Yamamoto, Tohru Tokunaga
    Pages 11-19

  4. Mechanisms of immune stimulation by bacterial DNA

    • David S. Pisetsky
    Pages 21-33

  5. Activation of NK cell (human and mouse) by immunostimulatory DNA sequence

    • Saburo Yamamoto, Toshiko Yamamoto, Sumiko Iho, Tohru Tokunaga
    Pages 35-43

  6. Activation of skin dendritic cells by immunostimulatory DNA

    • Jonathan C. Vogel, Mark C. Udey
    Pages 45-54

  7. Rescue of B cells from apoptosis by immune stimulatory CpG DNA

    • Arthur M. Krieg, Ae-Kyung Yi
    Pages 55-61

  8. The response of human B lymphocytes to oligodeoxynucleotides

    • Hua Liang, Peter E. Lipsky
    Pages 63-75

  9. Multiple effects of immunostimulatory DNA on T cells and the role of type I interferons

    • Siquan Sun, Xiaohong Zhang, David Tough, Jonathan Sprent
    Pages 77-84

  10. Pre-priming: a novel approach to DNA-based vaccination and immunomodulation

    • Hiroko Kobayashi, Anthony A. Horner, Elena Martin-Orozco, Eyal Raz
    Pages 85-96

  11. Signal transduction induced by immunostimulatory CpG DNA

    • Arthur M. Krieg
    Pages 97-105

  12. Immunostimulatory DNA sequences and cancer therapy

    • George J. Weiner
    Pages 107-116

  13. Modulation of asthmatic response by immunostimulatory DNA sequences

    • David Broide, Jae Youn Cho, Marina Miller, Jyothi Nayar, Greg Stachnick, Diego Castaneda et al.
    Pages 117-124

  14. The role of CpG in DNA vaccines

    • Michael J. McCluskie, Risini D. Weeratna, Heather L. Davis
    Pages 125-132

  15. Mucosal adjuvanticity of immunostimulatory DNA sequences

    • Anthony A. Horner, Nadya Cinman, Arash Ronaghy, Eyal Raz
    Pages 133-146

  16. Immunostimulatory DNA sequences help to eradicate intracellular pathogens

    • Hermann Wagner, Hans Häcker, Grayson B. Lipford
    Pages 147-152

  17. The antigenic properties of bacterial DNA in normal and aberrant immunity

    • David S. Pisetsky
    Pages 153-166

  18. The role of immunostimulatory CpG-DNA in septic shock

    • Hermann Wagner, Grayson B. Lipford, Hans Häcker
    Pages 167-171

  19. Activation of the innate immune system by CpG oligodeoxynucleotides: immunoprotective activity and safety

    • Dennis M. Klinman, Soren Kamstrup, Daniela Verthelyi, Ihsan Gursel, Ken J. Ishii, Fumihiko Takeshita et al.
    Pages 173-183
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Keywords

About this book

This volume is a product of a collaborative effort and attempts to provide a wide and up-to-date coverage of information regarding the biology and on the potential application of immunostimulatory DNA. ISS hold great promise for influencing the immune response and the authors anticipate that the high efficacy and low toxicity observed in animal models will translate into success in a variety of human clinical applications.

Editors and Affiliations

  • Dept. of Medicine-0663, University of California, San Diego, La Jolla, USA

    Eyal Raz

Bibliographic Information

  • Book Title: Immunostimulatory DNA Sequences

  • Editors: Eyal Raz

  • DOI: https://doi.org/10.1007/978-3-642-56866-4

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2001

  • Hardcover ISBN: 978-3-540-67749-9Published: 15 August 2000

  • Softcover ISBN: 978-3-642-63212-9Published: 21 October 2012

  • eBook ISBN: 978-3-642-56866-4Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: VIII, 183

  • Topics: Immunology

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