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Epstein-Barr Virus and Human Cancer

  • Book
  • © 2001

Overview

Editors:
  1. Kenzo Takada

    1. Institute for Genetic Medicine, Department of Tumor Virology, Hokkaido University, Sapporo, Japan

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Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 258)

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Table of contents (14 chapters)

  1. Front Matter

    Pages I-IX
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  2. Molecular Mechanisms of Maintenance and Disruption of Virus Latency

    1. Front Matter

      Pages 1-1
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    2. EBV’s Plasmid Replicon: An Enigma in cis and trans

      • B. Sugden, E. R. Leight
      Pages 3-11

    3. Replication Licensing of the EBV oriP Minichromosome

      • K. Hirai, M. Shirakata
      Pages 13-33

    4. Epstein-Barr Virus Nuclear Protein 2-Induced Activation of the EBV-Replicative Cycle in Akata Cells: Analysis by Tetracycline-Regulated Expression

      • S. Fujiwara
      Pages 35-50

    5. Two Epstein-Barr Virus Glycoprotein Complexes

      • L. M. Hutt-Fletcher, C. M. Lake
      Pages 51-64

    6. EBV Replication Enzymes

      • T. Tsurumi
      Pages 65-87

  3. EBV-Associated Malignancies

    1. Front Matter

      Pages 89-89
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    2. Pathology and Molecular Pathology of Epstein-Barr Virus-Associated Gastric Carcinoma

      • M. Fukayama, J.-M. Chong, H. Uozaki
      Pages 91-102

    3. EBV and Malignant Lymphoma with Special Emphasis on Pyothorax-Associated Lymphoma

      • K. Aozasa, H. Kanno, H. Miwa, Y. Tomita
      Pages 103-120

    4. AIDS Lymphoma: Its Virological Aspects

      • H. Katano, T. Sata, S. Mori
      Pages 121-138

  4. Molecular Mechanisms of Oncogenesis

    1. Front Matter

      Pages 139-139
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    2. Role of Epstein-Barr Virus in Burkitt’s Lymphoma

      • K. Takada
      Pages 141-151

    3. EBV Regulates c-MYC, Apoptosis, and Tumorigenicity in Burkitt’s Lymphoma

      • I. K. Ruf, P. W. Rhyne, H. Yang, C. M. Borza, L. M. Hutt-Fletcher, J. L. Cleveland et al.
      Pages 153-160

    4. Epstein-Barr Virus Infection of Human Epithelial Cells

      • S. Imai, J. Nishikawa, M. Kuroda, K. Takada
      Pages 161-184

    5. Characterization of EBV-Infected Epithelial Cell Lines from Gastric Cancer-Bearing Tissues

      • T. Sairenji, M. Tajima, M. Kanamori, N. Takasaka, X. Gao, M. Murakami et al.
      Pages 185-198

  5. Animal Model and New Therapeutic Approach to Malignancy

    1. Front Matter

      Pages 199-199
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    2. A New Animal Model for Epstein-Barr Virus Pathogenesis

      • F. Wang
      Pages 201-219

    3. Adoptive Immunotherapy of EBV-Associated Malignancies with EBV-Specific Cytotoxic T-Cell Lines

      • C. M. Rooney, L. K. Aguilar, M. H. Huls, M. K. Brenner, H. E. Heslop
      Pages 221-229

  6. Back Matter

    Pages 231-236
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Keywords

About this book

In this book, outstanding researchers from the US and Japan review recent progress in Epstein-Barr virus research. Most people carry EBV in memory B-cells in a latent stage. Many malignancies such as T/NK cell lymphoma, AIDS-associated B-cell lymphoma, gastric carcinoma and Hodgkin's disease have been causally linked to EBV. The development of molecular biology technique has allowed us to study the roles of individual EBV genes that act in the maintenance and disruption of EBV latency.

Editors and Affiliations

  • Institute for Genetic Medicine, Department of Tumor Virology, Hokkaido University, Sapporo, Japan

    Kenzo Takada

Bibliographic Information

  • Book Title: Epstein-Barr Virus and Human Cancer

  • Editors: Kenzo Takada

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-642-56515-1

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2001

  • Hardcover ISBN: 978-3-540-41506-0Published: 22 May 2001

  • Softcover ISBN: 978-3-642-62568-8Published: 05 November 2012

  • eBook ISBN: 978-3-642-56515-1Published: 06 December 2012

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: IX, 236

  • Topics: Microbiology, Virology, Oncology

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