Skip to main content
SpringerLink
Log in
Book cover

Arenaviruses II

The Molecular Pathogenesis of Arenavirus Infections

  • Book
  • © 2002

Overview

Editors:
  1. Michael B. A. Oldstone

    1. Division of Virology Department of Neuropharmacology, The Scripps Research Institute, La Jolla, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 263)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (12 chapters)

  1. Front Matter

    Pages I-XVII
    Download chapter PDF

  2. Lymphocytic Choriomeningitis Virus and Immunology

    • R. M. Zinkernagel
    Pages 1-5

  3. Innate Immune Responses to LCMV Infections: Natural Killer Cells and Cytokines

    • C. A. Biron, K. B. Nguyen, G. C. Pien
    Pages 7-27

  4. Bystander T Cell Activation and Attrition

    • J. M. McNally, R. M. Welsh
    Pages 29-41

  5. Immunocytotherapy

    • D. Homann
    Pages 43-65

  6. Mechanisms of Humoral Immunity Explored Through Studies of LCMV Infection

    • M. K. Slifka
    Pages 67-81

  7. Biology and Pathogenesis of Lymphocytic Choriomeningitis Virus Infection

    • M. B. A. Oldstone
    Pages 83-117

  8. Contribution of LCMV Transgenic Models to Understanding T Lymphocyte Development, Activation, Tolerance, and Autoimmunity

    • L. T. Nguyen, M. F. Bachmann, P. S. Ohashi
    Pages 119-143

  9. Regulation of Virally Induced Autoimmunity and Immunopathology: Contribution of LCMV Transgenic Models to Understanding Autoimmune Insulin-Dependent Diabetes Mellitus

    • M. G. von Herrath
    Pages 145-175

  10. LCMV and the Central Nervous System: Uncovering Basic Principles of CNS Physiology and Virus-Induced Disease

    • C. F. Evans, J. M. Redwine, C. E. Patterson, S. Askovic, G. F. Rall
    Pages 177-195

  11. Contribution of LCMV Towards Deciphering Biology of Quasispecies In Vivo

    • N. Sevilla, E. Domingo, J. C. de la Torre
    Pages 197-220

  12. Designing Arenaviral Vaccines

    • J. L. Whitton
    Pages 221-238

  13. Junin Virus Vaccines

    • D. A. Enria, J. G. Barrera Oro
    Pages 239-261

  14. Back Matter

    Pages 263-270
    Download chapter PDF
Back to top

Keywords

About this book

Viruses are studied either because they cause significant human, animal or plant disease or because they are useful materials for probing basic phenomena in biology, chemistry, genetics and/or molecular biology. Arenaviruses are unusually interesting in that they occupy both categories. Arenaviruses cause several human diseases known primarily as the hemorrhagic fevers occurring in South and Latin America (Bolivia: Machupo, Argentine, Junin virus, and Brazil: Sabia virus) and in Africa (Lassa fever virus). Because such viruses produce profound disabilities and often kill the persons they infect, they are a source of health concern and economic hardship in the countries where they are prevalent. Further, they provide new problems for healthcare persons owing to the narrowing of the world as visitors from many countries travel increasingly to and from endemic areas and may incubate the infectious agent taking it from an endemic area into an area where the virus is not expected. Such cases are now being re­ corded with increasing frequency. In addition to these hemor­ rhagic fever viruses, the arenavirus lymphocytic choriomeningitis virus (LCMV) can infect humans worldwide, although the illness is most often less disabling and severe than those elicited by the other arenaviruses. Yet, LCMV is of greater concern to non­ arenavirologists and experimentalists using tissue culture or ani­ mals, etc. , because normal-appearing cultured cells or tissues from animals used for research may be persistently infected with LCMV without manifesting clinical disease or cytopathology and may transmit that infection to laboratory workers.

Editors and Affiliations

  • Division of Virology Department of Neuropharmacology, The Scripps Research Institute, La Jolla, USA

    Michael B. A. Oldstone

Bibliographic Information

  • Book Title: Arenaviruses II

  • Book Subtitle: The Molecular Pathogenesis of Arenavirus Infections

  • Editors: Michael B. A. Oldstone

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-642-56055-2

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2002

  • Hardcover ISBN: 978-3-540-42705-6Published: 26 February 2002

  • Softcover ISBN: 978-3-642-62724-8Published: 21 October 2012

  • eBook ISBN: 978-3-642-56055-2Published: 06 December 2012

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: XVII, 270

  • Topics: Virology

Publish with us

Policies and ethics

Back to top

Search

Navigation