Overview
- Concise overview over the molecular basis of brain development
- Systematic description of the major classes of neuronal guidance molecules
- Includes supplementary material: sn.pub/extras
Part of the book series: Progress in Molecular and Subcellular Biology (PMSB, volume 32)
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Table of contents (6 chapters)
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Front Matter
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Back Matter
Keywords
About this book
Many complex molecular interactions are involved in the development of the mammalian brain. Molecules serving as guidance cues for migratory cells, growing axons and for recognition of postsynaptic targets are a major topic for research because they are directly involved in the formation of neuronal circuits, thus creating the foundation for subsequent functional refinement through interactions with the environment. In addition, most guidance cue molecules are also involved in plasticity, damage repair and regeneration in the adult brain.
This volume reviews current knowledge on major classes of molecules involved in: guidance of growing axons; tau proteins involved in the establishment of axonal polarity, outgrowth and contact recognition; gangliosides and lectins involved in neuronal migration, neurite outgrowth and contact recognition; and myelin molecules that inhibit nerve regeneration.
Editors and Affiliations
Bibliographic Information
Book Title: Guidance Cues in the Developing Brain
Editors: Ivica Kostović
Series Title: Progress in Molecular and Subcellular Biology
DOI: https://doi.org/10.1007/978-3-642-55557-2
Publisher: Springer Berlin, Heidelberg
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eBook Packages: Springer Book Archive
Copyright Information: Springer-Verlag Berlin Heidelberg 2003
Hardcover ISBN: 978-3-540-00117-1Published: 24 March 2003
Softcover ISBN: 978-3-642-62426-1Published: 14 September 2012
eBook ISBN: 978-3-642-55557-2Published: 06 December 2012
Series ISSN: 0079-6484
Series E-ISSN: 2197-8484
Edition Number: 1
Number of Pages: XII, 145
Topics: Neurobiology, Cell Biology, Developmental Biology