Editors:
- Addresses most interesting questions and applications enabled by high dimensional flow cytometry
- Reviews current practical approaches used to perform mass cytometry experiments
- Covers key bioinformatic techniques developed to facilitate analysis of data sets involving dozens of parameters in millions of single cells
- Includes supplementary material: sn.pub/extras
Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 377)
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Table of contents (10 chapters)
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Front Matter
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Back Matter
About this book
This volume highlights the most interesting biomedical and clinical applications of high-dimensional flow and mass cytometry. It reviews current practical approaches used to perform high-dimensional experiments and addresses key bioinformatic techniques for the analysis of data sets involving dozens of parameters in millions of single cells. Topics include single cell cancer biology; studies of the human immunome; exploration of immunological cell types such as CD8+ T cells; decipherment of signaling processes of cancer; mass-tag cellular barcoding; analysis of protein interactions by proximity ligation assays; Cytobank, a platform for the analysis of cytometry data; computational analysis of high-dimensional flow cytometric data; computational deconvolution approaches for the description of intracellular signaling dynamics and hyperspectral cytometry. All 10 chapters of this book have been written by respected experts in their fields. It is an invaluable reference book for both basic and clinical researchers.
Editors and Affiliations
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Center for Clinical Sciences Research, Department of Microbiology and Immunology, Stanford School of Medicine, Stanford, USA
Harris G. Fienberg, Garry P. Nolan
Bibliographic Information
Book Title: High-Dimensional Single Cell Analysis
Book Subtitle: Mass Cytometry, Multi-parametric Flow Cytometry and Bioinformatic Techniques
Editors: Harris G. Fienberg, Garry P. Nolan
Series Title: Current Topics in Microbiology and Immunology
DOI: https://doi.org/10.1007/978-3-642-54827-7
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2014
Hardcover ISBN: 978-3-642-54826-0Published: 08 May 2014
Softcover ISBN: 978-3-662-51267-8Published: 23 August 2016
eBook ISBN: 978-3-642-54827-7Published: 22 April 2014
Series ISSN: 0070-217X
Series E-ISSN: 2196-9965
Edition Number: 1
Number of Pages: X, 215
Number of Illustrations: 1 b/w illustrations, 67 illustrations in colour
Topics: Immunology, Cancer Research, Biological Techniques, Bioinformatics