Blood Replacement

1. Front Matter

   Pages I-XII

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2. Introduction

   1. Introduction

      • Ulrich F. Gruber

      Pages 1-3

3. Pathophysiology of Blood Loss

   1. Pathophysiology of Hemorrhagic Shock

      • Ulrich F. Gruber

      Pages 4-6

   2. Spontaneous Regulation Processes of the Organism Following Blood Loss

      • Ulrich F. Gruber

      Pages 6-8

   3. Problems of Oxygen Transport

      • Ulrich F. Gruber

      Pages 8-17

   4. Summary and Conclusions: Pathophysiology of Blood Loss

      • Ulrich F. Gruber

      Pages 17-18

4. Various Methods of Volume Replacement

   1. Volume Replacement Using Blood

      • Ulrich F. Gruber

      Pages 19-40

   2. Volume Replacement with Plasma

      • Ulrich F. Gruber

      Pages 40-48

   3. Volume Replacement with Artificial Colloid-Containing Infusion Solutions

      • Ulrich F. Gruber

      Pages 48-146

   4. Volume Replacement with Colloid-free Solutions

      • Ulrich F. Gruber

      Pages 146-155

5. Discussion

   1. Oral Therapy

      • Ulrich F. Gruber

      Pages 156-157

   2. Intra-arterial Infusion

      • Ulrich F. Gruber

      Pages 157-157

   3. Hemoglobin, Oxygen Transport

      • Ulrich F. Gruber

      Pages 157-161

   4. Shock Models

      • Ulrich F. Gruber

      Pages 161-163

   5. Problems of Blood Volume Determination

      • Ulrich F. Gruber

      Pages 163-164

   6. Colloid Osmotic Pressure, Filtration, Interstitial Pressure

      • Ulrich F. Gruber

      Pages 164-166

   7. Comparison of the Various Possibilities which are Available for Replacement of Blood Loss

      • Ulrich F. Gruber

      Pages 166-168

   8. Dextran or Gelatin?

      • Ulrich F. Gruber

      Pages 168-175

   9. Practical Conclusions

      • Ulrich F. Gruber

      Pages 175-175

   10. Concluding Remarks

       • Ulrich F. Gruber

       Pages 175-176

The manifold problems of shock are still of great importance, diagnostic and therapeutic experience of the "severely ill" being supplied with new information almost every month. In the 5 periodicals which have found their way to my desk during the past few days there are no less than 10 interesting articles on questions concerning shock research [see Bibliography 41 b, 53 a, 60 a, 192 a, 242 a, 350 b, 810 a, 941 a, 1069 a, 1082 a]. The most urgent point still is to maintain as complete as possible the objective catalog of the various shock manifestations found in man and in animals - yet at the same time to view interpretations of these phenomena in their relative and temporal "truth". Problems of shock research are not only interesting for their scientific value but also for their clinical implication. In particular, almost every practicing physician is facing problems of blood replacement very frequent­ ly. The effective or circulating blood volume remains an important theoret­ ical and therapeutic problem in the shock field. For years, U. F. GRUBER has pursued this question clinically and experimentally. This volume deals with the world literature in an exceptionally thorough manner. This book is made more than a compilation by including a long list of original work done with F. D. MOORE in Boston, in the Surgical Department in Chur, with 1. E. GELIN and S. E.

• blood
• research
• shock

• Department of Surgery, University of Basel, Bürgerspital Basel, Switzerland

  Ulrich F. Gruber

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