Skip to main content
SpringerLink
Log in

Genes and Environment in Cancer

  • Conference proceedings
  • © 1998

Overview

Editors:
  1. Manfred Schwab

    1. Abteilung Zytogenetik, Deutsches Krebsforschungszentrum, Heidelberg, Germany

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Hartmut M. Rabes

    1. Pathologisches Institut, Universität München, München, Germany

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  3. Klaus Munk

    1. Deutsches Krebsforschungszentrum, Heidelberg, Germany

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  4. Hans Peter Hofschneider

    1. Max-Planck-Institut für Biochemie, Martinsried, Germany

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Recent Results in Cancer Research (RECENTCANCER, volume 154)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (26 papers)

  1. Front Matter

    Pages I-XIV
    Download chapter PDF

  3. Risk Assessment and DNA Lesions

    1. Front Matter

      Pages 37-37
      Download chapter PDF

    2. Molecular Epidemiology of Environmental Carcinogenesis

      • F. P. Perera
      Pages 39-46

    3. Polymorphisms of N-Acetyltransferases, Glutathione S-Transferases, Microsomal Epoxide Hydrolase and Sulfotransferases: Influence on Cancer Susceptibility

      • J. G. Hengstler, M. Arand, M. E. Herrero, F. Oesch
      Pages 47-85

    4. Impact of Adduct Determination on the Assessment of Cancer Susceptibility

      • H. Bartsch, M. Rojas, K. Alexandrov, A. Risch
      Pages 86-96

    5. Mutation Spectra Resulting from Carcinogenic Exposure: From Model Systems to Cancer-Related Genes

      • E. Dogliotti, P. Hainaut, T. Hernandez, M. D’Errico, D. M. Demarini
      Pages 97-124

  4. DNA Repair and Genetic Susceptibility

    1. Front Matter

      Pages 125-125
      Download chapter PDF

    2. Relevance of DNA Repair to Carcinogenesis and Cancer Therapy

      • M. F. Rajewsky, J. Engelbergs, J. Thomale, T. Schweer
      Pages 127-146

    3. Molecular Basis of DNA Repair Mechanisms and Syndromes

      • G. Weeda, J. de Boer, I. Donker, J. de Wit, S. B. Winkler, G. T. J. van der Horst et al.
      Pages 147-155

    4. The Ataxia Telangiectasia Gene in Familial and Sporadic Cancer

      • M. A. R. Yuille, L. J. A. Coignet
      Pages 156-173

  5. Induced Chromosome Damage and Cancer

    1. Front Matter

      Pages 175-175
      Download chapter PDF

    2. Cancer Predictive Value of Cytogenetic Markers Used in Occupational Health Surveillance Programs

      • L. Hagmar, S. Bonassi, U. Strömberg, Z. Mikoczy, C. Lando, I.-L. Hansteen et al.
      Pages 177-184

    3. Instability at Chromosomal Fragile Sites

      • T. W. Glover
      Pages 185-199

    4. The Role of Deletions at the FRA3B/FHIT Locus in Carcinogenesis

      • K. Huebner, T. Druck, Z. Siprashvili, C. M. Croce, A. Kovatich, P. A. McCue
      Pages 200-215

    5. Gene Amplification Mechanisms: The Role of Fragile Sites

      • M. Debatisse, A. Coquelle, F. Toledo, G. Buttin
      Pages 216-226

  6. Genetic Susceptibility and Environmental Exposure: “The RET Paradigm”

    1. Front Matter

      Pages 227-227
      Download chapter PDF

    2. Mechanisms of Development of Multiple Endocrine Neoplasia Type 2 and Hirschsprung’s Disease by ret Mutations

      • M. Takahashi, N. Asai, T. Iwashita, H. Murakami, S. Ito
      Pages 229-236
Back to top

Keywords

About this book

Different cancer types can result from a multiplicity of genetic and environmental factors. In recent years a number of genes have been identified as strong determinants for particular forms of cancer (particularly colon and breast cancer). The incomplete penetrance often evinced by the mutations of these genes has raised the possibility that additional endogenous or exogenous determinants contribute to cancer development or suppression. The major aim of this book is to present an integrated view of the various environmental, epidemiological and genetic determinants that contribute to a disease syndrome collectively known as "cancer".

Editors and Affiliations

  • Abteilung Zytogenetik, Deutsches Krebsforschungszentrum, Heidelberg, Germany

    Manfred Schwab

  • Pathologisches Institut, Universität München, München, Germany

    Hartmut M. Rabes

  • Deutsches Krebsforschungszentrum, Heidelberg, Germany

    Klaus Munk

  • Max-Planck-Institut für Biochemie, Martinsried, Germany

    Hans Peter Hofschneider

Bibliographic Information

  • Book Title: Genes and Environment in Cancer

  • Editors: Manfred Schwab, Hartmut M. Rabes, Klaus Munk, Hans Peter Hofschneider

  • Series Title: Recent Results in Cancer Research

  • DOI: https://doi.org/10.1007/978-3-642-46870-4

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin · Heidelberg 1998

  • Softcover ISBN: 978-3-642-46872-8Published: 01 March 2012

  • eBook ISBN: 978-3-642-46870-4Published: 06 December 2012

  • Series ISSN: 0080-0015

  • Series E-ISSN: 2197-6767

  • Edition Number: 1

  • Number of Pages: XIV, 368

  • Number of Illustrations: 8 illustrations in colour

  • Topics: Oncology, Human Genetics

Publish with us

Policies and ethics

Back to top

Search

Navigation