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Mechanism of Action of Antimicrobial and Antitumor Agents

  • Book
  • © 1975

Overview

Editors:
  1. John W. Corcoran

    1. Department of Biochemistry, The Medical and Dental Schools, Northwestern University, Chicago, USA

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  2. Fred E. Hahn

    1. Department of the Army, Walter Reed Army Institute of Research, Walter Reed Army Medical Center, USA

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  3. J. F. Snell
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  4. K. L. Arora
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Part of the book series: Antibiotics (ANTIBIOTICS, volume 3)

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Table of contents (47 chapters)

  1. Front Matter

    Pages I-XII
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  2. Interference with Nucleic Acid Biosynthesis

    1. Front Matter

      Pages 1-1
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    2. Anthramycin

      • Kurt W. Kohn
      Pages 3-11

    3. 3′-Amino-3′-Deoxyadenosine

      • Harold T. Shigeura
      Pages 12-20

    4. Bleomycin

      • Hamao Umezawa
      Pages 21-33

    5. Berenil: A Trypanocide with Selective Activity against Extranuclear DNA

      • B. A. Newton
      Pages 34-47

    6. Camptothecin

      • Susan B. Horwitz
      Pages 48-57

    7. Chloroquine (Resochin)

      • Fred E. Hahn
      Pages 58-78

    8. Distamycin A and Netropsin

      • Fred E. Hahn
      Pages 79-100

    9. Daunomycin (Daunorubicin) and Adriamycin and Structural Analogues: Biological Activity and Mechanism of Action

      • A. Di Marco, F. Arcamone, F. Zunino
      Pages 101-128

    10. Edeines

      • Z. Kurylo-Borowska
      Pages 129-140

    11. Ethidium and Propidium

      • Michael Waring
      Pages 141-165

    12. Kanchanomycin

      • Irving H. Goldberg
      Pages 166-173

    13. Nalidixic Acid—Mode of Action

      • William A. Goss, Thomas M. Cook
      Pages 174-196

    14. Olivomycin, Chromomycin, and Mithramycin

      • G. F. Gause
      Pages 197-202

    15. Quinacrine and Other Acridines

      • Alan David Wolfe
      Pages 203-233

    16. Quinoxaline Antibiotics

      • Ken Katagiri, Tadashi Yoshida, Kosaburo Sato
      Pages 234-251

    17. Rifamycins and Other Ansamycins

      • W. Wehrli, M. Staehelin
      Pages 252-268

    18. Sibiromycin

      • G. F. Gause
      Pages 269-273

    19. Thiaxanthenones: Miracil D and Hycanthone

      • Erich Hirschberg
      Pages 274-302
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Keywords

About this book

This volume is the third in the series devoted to Antibiotics initiated by Springer Verlag in 1967. The first two volumes were devoted to the Mode of Action of Antibiotics and Biogenesis, respectively and were received graciously. During the intervening years these two works have been used often by research workers and students alike and have been quoted extensively. Although a number of other excellent treatises on antibiotics have appeared, the Springer series has set a standard for thoroughness and quality that meets the need of the scientific community. It is against this background that the present Editors set about the preparation of a third volume in the Series on Antibiotics. Since the appearance of Volume I, also dealing with Mechanism of Action, tremendous strides have been made in the depth and breadth of our knowledge of molecular biology, microbial chemistry and molecular pharmacology and of their direct application to studies on the mode of action of drugs. The field of molecular biology itself was in its relative infancy during the preceding decade and the unique role played by many anti­ biotics in the development of our understanding of nucleic acid synthesis and function and its relationship to protein synthesis and cell physiology has led rapidly to a very precise, understanding of how many of these same antibiotics inhibit susceptible cells.

Editors and Affiliations

  • Department of Biochemistry, The Medical and Dental Schools, Northwestern University, Chicago, USA

    John W. Corcoran

  • Department of the Army, Walter Reed Army Institute of Research, Walter Reed Army Medical Center, USA

    Fred E. Hahn

Bibliographic Information

  • Book Title: Mechanism of Action of Antimicrobial and Antitumor Agents

  • Editors: John W. Corcoran, Fred E. Hahn, J. F. Snell, K. L. Arora

  • Series Title: Antibiotics

  • DOI: https://doi.org/10.1007/978-3-642-46304-4

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1975

  • Softcover ISBN: 978-3-642-46306-8Published: 29 March 2012

  • eBook ISBN: 978-3-642-46304-4Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XII, 744

  • Topics: Microbiology, Medical Microbiology

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