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Topics and Perspectives in Adenosine Research

Proceedings of the 3rd International Symposium on Adenosine, Munich, June 1986

  • Conference proceedings
  • © 1987

Overview

Editors:
  1. Eckehart Gerlach

    1. Physiologisches Institut, Universität München, München 2, Federal Republic of Germany

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  2. Bernhard Friedrich Becker

    1. Physiologisches Institut, Universität München, München 2, Federal Republic of Germany

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Table of contents (53 papers)

  1. Front Matter

    Pages I-XIV
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  2. Adenosine Receptors and Nucleoside Transporter

    1. Front Matter

      Pages 1-1
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    2. Agonist and Antagonist Radioligands and Photoaffinity Labels for the Adenosine A1 Receptor

      • J. Linden, C. Q. Earl, A. Patel, R. H. Craig, S. M. Daluge
      Pages 3-14

    3. Functional Characterization of A1 Adenosine Receptors by Photoaffinity Labelling

      • M. J. Lohse, K.-N. Klotz, U. Schwabe
      Pages 15-22

    4. Analogues of Adenosine, Theophylline, and Caffeine: Selective Interactions with A1 and A2 Adenosine Receptors

      • J. W. Daly, D. Ukena, K. A. Jacobson
      Pages 23-36

    5. Structural Studies on Adenosine Ri Receptors from Rat Cerebral Cortex

      • E. Perez-Reyes, S.-M. H. Yeung, R. L. Lasher, D. M. F. Cooper
      Pages 37-48

    6. Biochemical and Autoradiographic Approaches to the Characterization of Adenosine Receptors in Brain

      • M. Reddington, S. P. Alexander, A. Erfurth, K. S. Lee, G. W. Kreutzberg
      Pages 49-58

    7. Adenosine Receptor Subtypes: Binding Studies

      • R. F. Bruns, G. H. Lu, T. A. Pugsley
      Pages 59-73

    8. Central Sites of Adenosine Action and Their Interaction with Various Drugs

      • P. J. Marangos, J. Deckert, J.-C. Bisserbe
      Pages 74-88

    9. Nucleoside Transport Inhibition In Vitro and In Vivo

      • A. R. P. Paterson, E. S. Jakobs, C. Y. C. Ng, R. D. Odegard, A. A. Adjei
      Pages 89-101

    10. Kinetic and Molecular Properties of Nucleoside Transporters in Animal Cells

      • S. M. Jarvis
      Pages 102-117

    11. Drug Interactions with Nucleoside Transport Systems

      • A. S. Clanachan, T. P. Heaton, F. E. Parkinson
      Pages 118-130

  3. Adenosine Formation, Metabolism and Transport

    1. Front Matter

      Pages 131-131
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    2. Regulation and Function of 5′-Nucleotidases

      • A. R. Collinson, K. J. Peuhkurinen, J. M. Lowenstein
      Pages 133-144

    3. Kinetics of Endothelial Cell Ectonucleotidases

      • J. D. Pearson, S. B. Coade
      Pages 145-154

    4. Critical Evaluation of the Role of Ecto- and Cytosolic 5′-Nucleotidase in Adenosine Formation

      • A. C. Newby, Y. Worku, P. Meghji
      Pages 155-169

    5. New Insights into the Mechanism of Myocardial Adenosine Formation

      • A. Dendorfer, S. Lauk, A. Schaff, S. Nees
      Pages 170-187

    6. Cardiac Myocyte and Coronary Endothelial Cell Adenosine Transport

      • M. J. Rovetto, D. A. Ford, A. Yassin
      Pages 188-198

    7. The Importance of the Transmethylation Pathway for Adenosine Metabolism in the Heart

      • H. G. E. Llyod, J. Schrader
      Pages 199-208

    8. Uric Acid, the Major Catabolite of Cardiac Adenine Nucleotides and Adenosine, Originates in the Coronary Endothelium

      • B. F. Becker, E. Gerlach
      Pages 209-222
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Keywords

About this book

An "International Conference on Physiological and Regulatory Functions of Adenosine and Adenine Nucleotides" was held in Banff, Canada, in June 1978. Four years later, in June 1982, an "International Symposium on Adenosine" took place in Charlottesville, Virginia, USA. Both meetings revealed an increasing interest of scientists from numerous disciplines on biochemical, physiological and pathophysiological aspects of adenosine as a proposed mediator of various specified regulatory functions, both on the cellular and organ level. In view of the obvious continuity of adenosine research in well-established and newly emerging fields, a scientific committee was charged with organizing a further meeting to be held in Munich, Germany, in June 1986. Members of the committee were H. P. Baer, Canada, R. M. Berne, USA, and E. Gerlach, G. W. Kreutzberg and J. Schrader, FRG. It was the general intention that in this conference, purposely named "3rd International Symposium on Adenosine", emphasis should be placed on the presentation of shorter reports concerning both latest as well as controversial aspects and developments in as wide a scope of adenosine research as possible. Therefore, in addition to more than 50 presentations by invited speakers, over 120 posters were displayed. Coinciding with the symposium, abstracts of all contributions were published in Pfltigers Archiv - European Journal of Physiology [Vol. 407, Suppl. 1, 1986]. This book, entitled "Topics and Perspectives in Adenosine Research", now enholds all papers presented at the 3rd International Symposium on Adenosine, together with the complete discussions following each talk.

Editors and Affiliations

  • Physiologisches Institut, Universität München, München 2, Federal Republic of Germany

    Eckehart Gerlach, Bernhard Friedrich Becker

Bibliographic Information

  • Book Title: Topics and Perspectives in Adenosine Research

  • Book Subtitle: Proceedings of the 3rd International Symposium on Adenosine, Munich, June 1986

  • Editors: Eckehart Gerlach, Bernhard Friedrich Becker

  • DOI: https://doi.org/10.1007/978-3-642-45619-0

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1987

  • Softcover ISBN: 978-3-642-45621-3Due: 14 March 2012

  • eBook ISBN: 978-3-642-45619-0Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XIV

  • Topics: Human Physiology, Biochemistry, general, Cardiology, Allergology, Immunology, Pharmacology/Toxicology

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