Micro-Segmented Flow

1. Front Matter

   Pages i-xvii

   PDF

2. Introduction

   • Brian P. Cahill

   Pages 1-3

3. Generation, Manipulation and Characterization of Micro Fluid Segments

   1. Front Matter

      Pages 5-5

      PDF

   2. Droplet Microfluidics in Two-Dimensional Channels

      • Charles N. Baroud

      Pages 7-29

   3. Electrical Switching of Droplets and Fluid Segments

      • Matthias Budden, Steffen Schneider, J. Michael Köhler, Brian P. Cahill

      Pages 31-54

   4. Chip-Integrated Solutions for Manipulation and Sorting of Micro Droplets and Fluid Segments by Electrical Actuation

      • Lars Dittrich, Martin Hoffmann

      Pages 55-72

   5. Electrical Sensing in Segmented Flow Microfluidics

      • Brian P. Cahill, Joerg Schemberg, Thomas Nacke, Gunter Gastrock

      Pages 73-100

4. Chemical Application in Micro Continuous-Flow Synthesis of Nanoparticles

   1. Front Matter

      Pages 101-101

      PDF

   2. Solid Particle Handling in Microreaction Technology: Practical Challenges and Application of Microfluid Segments for Particle-Based Processes

      • Frederik Scheiff, David William Agar

      Pages 103-148

   3. Micro Continuous-Flow Synthesis of Metal Nanoparticles Using Micro Fluid Segment Technology

      • Andrea Knauer, J. Michael Köhler

      Pages 149-200

5. Biological Application: Cell-Free Biotechnology, Cell Cultivation and Screening Systems

   1. Front Matter

      Pages 201-201

      PDF

   2. Characterization of Combinatorial Effects of Toxic Substances by Cell Cultivation in Micro Segmented Flow

      • J. Cao, D. Kürsten, A. Funfak, S. Schneider, J. M. Köhler

      Pages 203-230

   3. Screening for Antibiotic Activity by Miniaturized Cultivation in Micro-Segmented Flow

      • Emerson Zang, Miguel Tovar, Karin Martin, Martin Roth

      Pages 231-265

6. Back Matter

   Pages 267-272

   PDF

The book is dedicated to the method and application potential of micro segmented flow. The recent state of development of this powerful technique is presented in 12 chapters by leading researchers from different countries. In the first section, the principles of generation and manipulation of micro-fluidic segments are explained. In the second section, the micro continuous-flow synthesis of different types of nanomaterials is shown as a typical example for the use of advantages of the technique in chemistry. In the third part, the particular importance of the technique in biotechnical applications is presented demonstrating the progress for miniaturized cell-free processes, for molecular biology and DNA-based diagnostics and sequencing as well as for the development of antibiotics and the evaluation of toxic effects in medicine and environment.

• Automated Microfluidic Analysis
• Cell Screening Systems
• Cell-free Biotechnology
• Combinatorial Effects of Toxic Substances
• Continuous-Flow Synthesis of Nanoparticles
• Fluid Manipulation
• Micro Fluid Segment Technology
• Micro Reaction Technology
• Particle Handling
• Single Cell Analysis
• fluid- and aerodynamics

• Technical University Ilmenau Institute of Chemistry and Biotechnology, Ilmenau, Germany

  J. Michael Köhler

• Institute for Bioprocessing and Analytical Measurement Techniques, Heilbad Heiligenstadt, Germany

  Brian P. Cahill

Policies and ethics