Overview
- Establishes the basis of a 21st century approach to biological complexity
- Explores the Systems Biology of signaling networks, cellular structures and fluxes, organ and microorganism functions
- Broadens your understanding of biological phenomena, emphasizing interconnections and functional interrelationships
- Includes supplementary material: sn.pub/extras
Part of the book series: Springer Series in Biophysics (BIOPHYSICS, volume 16)
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Table of contents (13 chapters)
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Front Matter
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Systems Biology of Signaling Networks
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Front Matter
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Systems Biology of Cellular Structures and Fluxes
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Front Matter
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Systems Biology of Organ Function
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Front Matter
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Systems Biology of Microorganisms
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Front Matter
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Back Matter
Keywords
About this book
Systems Biology represents a new paradigm aiming at a whole-organism-level understanding of biological phenomena, emphasizing interconnections and functional interrelationships rather than component parts. The study of network properties, and how they control and regulate behavior from the cellular to organism level, constitutes a main focus of Systems Biology. This book addresses from a novel perspective a major unsolved biological problem: understanding how a cell works and what goes wrong in pathology. The task undertaken by the authors is in equal parts conceptual and methodological, integrative and analytical, experimental and theoretical, qualitative and quantitative, didactic and comprehensive. Essentially, they unravel the spatio-temporal unfolding of interacting mass-energy and information networks at the cellular and organ levels, as well as its modulation through activation or repression by signaling networks to produce a certain phenotype or (patho)physiological response.
Starting with the historical roots, in thirteen chapters this work explores the Systems Biology of signaling networks, cellular structures and fluxes, organ and microorganism functions. In doing so, it establishes the basis of a 21st century approach to biological complexity.
Editors and Affiliations
Bibliographic Information
Book Title: Systems Biology of Metabolic and Signaling Networks
Book Subtitle: Energy, Mass and Information Transfer
Editors: Miguel A. Aon, Valdur Saks, Uwe Schlattner
Series Title: Springer Series in Biophysics
DOI: https://doi.org/10.1007/978-3-642-38505-6
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag Berlin Heidelberg 2014
Hardcover ISBN: 978-3-642-38504-9Published: 04 November 2013
Softcover ISBN: 978-3-662-50835-0Published: 23 August 2016
eBook ISBN: 978-3-642-38505-6Published: 22 October 2013
Series ISSN: 0932-2353
Series E-ISSN: 1868-2561
Edition Number: 1
Number of Pages: X, 375
Number of Illustrations: 23 b/w illustrations, 67 illustrations in colour
Topics: Systems Biology, Computer Appl. in Life Sciences, Systems Biology, Metabolomics, Proteomics, Biological and Medical Physics, Biophysics