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Calcium signalling

Approaches and Findings in the Heart and Blood

  • Book
  • © 2013

Overview

Authors:
  1. Lars Kaestner

    1. , Institution für Molekulare Zellbiologie, Universität des Saarlandes, Homburg/Saar, Germany

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  • Broad topical coverage from general concepts to detailed examples

  • 96 Figures and 4 Tables

  • Includes latest developments and research results

  • Includes supplementary material: sn.pub/extras

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Table of contents (28 chapters)

  1. Front Matter

    Pages I-XI
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  2. Summary

    1. Front Matter

      Pages 1-1
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    2. Introduction

      • Lars Kaestner
      Pages 2-2

    3. Direct evidence - the digital approach

      • Lars Kaestner
      Pages 3-3

    4. Fluorescence-based visualisation

      • Lars Kaestner
      Pages 4-13

    5. Aequorin-based measurements

      • Lars Kaestner
      Pages 14-14

    6. Measurement of calcium transport across membranes

      • Lars Kaestner
      Pages 15-16

    7. Molecular biology based approaches

      • Lars Kaestner
      Pages 17-18

    8. Manipulation of calcium

      • Lars Kaestner
      Pages 19-20

    9. Calcium-induced function

      • Lars Kaestner
      Pages 21-23

    10. Calcium signalling in cardiac myocytes

      • Lars Kaestner
      Pages 24-25

    11. Calcium signalling in red blood cells

      • Lars Kaestner
      Pages 26-28

    12. Perspective

      • Lars Kaestner
      Pages 29-34

  4. Calcium Signalling in Cardiac Myocytes

    1. Front Matter

      Pages 93-93
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Keywords

About this book

The book combines general concepts and methods to investigate calcium signalling in cells ranging from molecular biology approaches to manipulation of calcium in living cells. The focus within these methods in on the broad range of fluorescence imaging technology, in particular on optical sectioning techniques and fast image acquisition. In addition to these general guidelines there are application examples in a context beyond calcium signalling in two major fields: investigations of isolated cardiac myocytes and red blood cell related research. While the cellular cardiology section provides snapshots of certain calcium signalling aspects, the red blood cell part presents an overview from the functional identification of calcium-channels to a concept of physiological and pathophysiological relevance.

Authors and Affiliations

  • , Institution für Molekulare Zellbiologie, Universität des Saarlandes, Homburg/Saar, Germany

    Lars Kaestner

About the author

Dr. Lars Kaestner: Universität des Saarlandes

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