Point-of-Care Diagnostics on a Chip

1. Front Matter

   Pages i-xv

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2. Fluid Handling

   1. Front Matter

      Pages 1-1

      PDF

   2. Low-Cost Microdevices for Point-of-Care Testing

      • Curtis D. Chin, Sau Yin Chin, Tassaneewan Laksanasopin, Samuel K. Sia

      Pages 3-21

   3. Programmable Hybrid Integrated Circuit/Microfluidic Chips

      • Caspar Floryan, David Issadore, Robert M. Westervelt

      Pages 23-43

3. Detection

   1. Front Matter

      Pages 45-45

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   2. Flow Cytometry on a Chip

      • Peter Kiesel, Joerg Martini, Michael I. Recht, Marshall W. Bern, Noble M. Johnson, Malte Huck

      Pages 47-69

   3. Lensfree Computational Microscopy Tools for On-Chip Imaging of Biochips

      • Serhan O. Isikman, Waheb Bishara, Onur Mudanyali, Ting-Wei Su, Derek Tseng, Aydogan Ozcan

      Pages 71-96

   4. Dielectric Detection Using Biochemical Assays

      • Yang-Kyu Choi, Chang-Hoon Kim, Jae-Hyuk Ahn, Jee-Yeon Kim, Sungho Kim

      Pages 97-123

   5. Semiconductor-Based Biosensing Chip for Point-of-Care Diagnostics

      • Toshiya Sakata

      Pages 125-152

   6. Magneto-Nanosensor Diagnostic Chips

      • Richard S. Gaster, Drew A. Hall, Shan X. Wang

      Pages 153-176

   7. Handheld NMR Systems and Their Applications for Biomolecular Sensing

      • Nan Sun, Donhee Ham

      Pages 177-196

   8. Diagnostic Magnetic Resonance Technology

      • Changwook Min, Huilin Shao, David Issadore, Monty Liong, Ralph Weissleder, Hakho Lee

      Pages 197-222

4. Back Matter

   Pages 223-226

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The topic of this book is the development of automated and inexpensive tools that transfer medical tests from a specialized clinical laboratory directly to the point of care, using biochip technology. Immediate access to medically relevant biochemical information for doctors and nurses promises to revolutionize patient care and dramatically lower costs. The miniaturization and automation of medical tests are made possible by biochip technology, that integrates advances in integrated circuits, microelectromechanical systems (MEMS), microfluidics, and electronics. The target audience for this book includes engineering and biomedical researchers who would like to develop or apply biochip technology. They can use this book as a review of the field and as a guide for the development of novel biochip technology for point of care medicine. This book can also be used as a teaching tool for engineering and biomedical students, as well as a reference for physicians and health professionals.

• biochip technology reviewed
• biochips
• biochips overview
• clinical laboratory medicine
• digital microfluidics
• holographic cell imaging
• lab-on-a-chip book
• medical diagnostics
• passive and active microfluidics
• point of care diagnostics
• single molecule detection

• , Department of Bioengineering, University of Pennsylvania, Philadelphia, USA

  David Issadore

• , School of Engineering, Applied Sciences, Harvard University, Cambridge, USA

  Robert M. Westervelt

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