Brain Imaging in Behavioral Neuroscience

1. Front Matter

   Pages i-x

   PDF

2. Food and Drug Reward: Overlapping Circuits in Human Obesity and Addiction

   • N. D. Volkow, G. J. Wang, J. S. Fowler, D. Tomasi, R. Baler

   Pages 1-24

3. Nonhuman Primate Models of Addiction and PET Imaging: Dopamine System Dysregulation

   • Robert W. Gould, Linda J. Porrino, Michael A. Nader

   Pages 25-44

4. PET Applications in Animal Models of Neurodegenerative and Neuroinflammatory Disorders

   • Makoto Higuchi, Jun Maeda, Bin Ji, Masaki Tokunaga, Ming-Rong Zhang, Masahiro Maruyama et al.

   Pages 45-64

5. Neural and Behavioral Endophenotypes in ADHD

   • Natalia del Campo, Ulrich Müller, Barbara J. Sahakian

   Pages 65-91

6. Experimental Protocols for Behavioral Imaging: Seeing Animal Models of Drug Abuse in a New Light

   • Alexandra R. Aarons, Amanda Talan, Wynne K. Schiffer

   Pages 93-115

7. Molecular Imaging and the Neuropathologies of Parkinson’s Disease

   • Paul Cumming, Per Borghammer

   Pages 117-148

8. Imaging of Seasonal Affective Disorder and Seasonality Effects on Serotonin and Dopamine Function in the Human Brain

   • Nicole Praschak-Rieder, Matthaeus Willeit

   Pages 149-167

9. Magnetic Resonance Spectroscopic Methods for the Assessment of Metabolic Functions in the Diseased Brain

   • Hélène Hall, Sandra Cuellar-Baena, Carina Dahlberg, René in’t Zandt, Vladimir Denisov, Deniz Kirik

   Pages 169-198

10. MR Spectroscopic Studies of the Brain in Psychiatric Disorders

    • Richard J. Maddock, Michael H. Buonocore

    Pages 199-251

11. fMRI as a Measure of Cognition Related Brain Circuitry in Schizophrenia

    • Laura A. Libby, J. Daniel Ragland

    Pages 253-267

12. MRI Studies in Late-Life Mood Disorders

    • Carmen Andreescu, Howard Aizenstein

    Pages 269-287

13. The Role of Diffusion Tensor Imaging in the Study of Cognitive Aging

    • Owen Carmichael, Samuel Lockhart

    Pages 289-320

14. Structural, Functional and Spectroscopic MRI Studies of Methamphetamine Addiction

    • Ruth Salo, Catherine Fassbender

    Pages 321-364

15. Pharmacological MRI Approaches to Understanding Mechanisms of Drug Action

    • Michael J. Minzenberg

    Pages 365-388

16. Back Matter

    Pages 389-391

    PDF

This volume highlights the remarkable new developments in brain imaging, including those that apply magnetic resonance imaging (MRI) and Positron Emission Tomography (PET), that allow us to non invasively study the living human brain in health and in disease. These technological advances have allowed us to obtain new and powerful insights into the structure and function of the healthy brain as it develops across the life cycle, as well as the molecular make up of brain systems and circuits as they develop and change with age. New brain imaging technologies have also given us new insights into the causes of many common brain disorders, including ADHD, schizophrenia, depression and Alzheimer’s disease, which collectively affect a large segment of the population. These new insights have major implications for understanding and treating these brain disorders, and are providing clinicians with the first ever set of biomarkers that can be used to guide diagnosis and monitor treatment effects. The advances in brain imaging over the last 20 years, summarized in this volume, represent a major advance in modern biomedical sciences.

• ADHD
• Parkinson's disease
• drug addiction
• magnetic resonance imaging
• positron emission tomography
• schizophrenia

• , UC Davis Imaging Center, University of California at Davis, Sacramento, USA

  Cameron S. Carter

• , Dep of Experimental Psychology/Dep of Ps, University of Cambridge, Cambridge, United Kingdom

  Jeffrey W. Dalley

Policies and ethics