Overview
- The objective of this CTMI volume is to provide readers with a foundation for understanding what ADARs are and how they fact to affect gene expression and product function.
- It is becoming increasingly apparent that ADARs may function not only as enzymes that deaminate adenosine in RNA substrates with double-stranded character, but also as RNA binding proteins independent of their catalytic property.
- Future studies of ADARs no doubt will provide us with additional surprises and new insights into the modulation of biological processes by the ADAR family of proteins
- Includes supplementary material: sn.pub/extras
Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 353)
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Table of contents (10 chapters)
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Front Matter
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Back Matter
Keywords
About this book
“The objective of this CTMI volume is to provide readers with a foundation for understanding what ADARs are and how they act to affect gene expression and function. It is becoming increasingly apparent that ADARs may possess roles not only as enzymes that deaminate adenosine to produce inosine in RNA substrates with double-stranded character, but also as proteins independent of their catalytic property. Because A-to-I editing may affect base-pairing and RNA structure, processes including translation, splicing, RNA replication, and miR and siRNA silencing may be affected. Future studies of ADARs no doubt will provide us with additional surprises and new insights into the modulation of biological processes by the ADAR family of proteins.”
Editors and Affiliations
Bibliographic Information
Book Title: Adenosine Deaminases Acting on RNA (ADARs) and A-to-I Editing
Editors: Charles E. Samuel
Series Title: Current Topics in Microbiology and Immunology
DOI: https://doi.org/10.1007/978-3-642-22801-8
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2012
Hardcover ISBN: 978-3-642-22800-1Published: 06 November 2011
Softcover ISBN: 978-3-642-42817-3Published: 26 January 2014
eBook ISBN: 978-3-642-22801-8Published: 06 November 2011
Series ISSN: 0070-217X
Series E-ISSN: 2196-9965
Edition Number: 1
Number of Pages: X, 238
Topics: Molecular Medicine, Human Physiology