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  • Book
  • © 2011

Histone Deacetylases: the Biology and Clinical Implication

  • Will certainly serve as a reference to catalyze new collaborations between experts within the HDAC field
  • Written by leading authorities in the field
  • With numerous illustrations

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 206)

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eBook USD 259.00
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  • Instant download
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Softcover Book USD 329.99
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  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
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Hardcover Book USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-xi
  2. K-Acetylation and Its Enzymes: Overview and New Developments

    • Juliette Adjo Aka, Go-Woon Kim, Xiang-Jiao Yang
    Pages 1-12
  3. The Biology of HDAC in Cancer: The Nuclear and Epigenetic Components

    • Astrid Hagelkruys, Anna Sawicka, Magdalena Rennmayr, Christian Seiser
    Pages 13-37
  4. HDACs in Skeletal Muscle Remodeling and Neuromuscular Disease

    • Bryan J. Simmons, Todd J. Cohen, Richard Bedlack, Tso-Pang Yao
    Pages 79-101
  5. Mitochondrial Sirtuins in the Regulation of Mitochondrial Activity and Metabolic Adaptation

    • David B. Lombard, Daniel X. Tishkoff, Jianjun Bao
    Pages 163-188
  6. Characterization of Nuclear Sirtuins: Molecular Mechanisms and Physiological Relevance

    • Debra Toiber, Carlos Sebastian, Raul Mostoslavsky
    Pages 189-224
  7. Sirtuin Modulators

    • Sumit S. Mahajan, Vid Leko, Julian A. Simon, Antonio Bedalov
    Pages 241-255
  8. Back Matter

    Pages 257-260

About this book

The book highlights work from many different labs that taught us abnormal HDACs potentially contribute to the development or progression of many human diseases including immune dysfunctions, heart disease, cancer, memory impairment, aging, and metabolic disorders.

Editors and Affiliations

  • , Department of Pharmacology, Duke University, Durham, USA

    Tso-Pang Yao

  • , Department of Molecular Oncology, H.Lee Moffitt Cancer Center & Research I, Tampa, USA

    Edward Seto

Bibliographic Information

Buy it now

Buying options

eBook USD 259.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 329.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access