Skip to main content
SpringerLink
Log in

Pediatric Clinical Pharmacology

  • Book
  • © 2011

Overview

Editors:
  1. Hannsjörg W. Seyberth

    1. Klinik für Kinder- und Jugendmedizin, Univ.Klinikum Marburg, Marburg, Germany

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Anders Rane

    1. Karolinska Institutet, Dept. Laboratory Medicine, Karolinska University Hostpital, Stockholm, Sweden

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  3. Matthias Schwab

    1. für Klinische Pharmakologie (IKP), Dr. Margarete Fischer-Bosch Institut, Stuttgart, Germany

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Written by international leading experts in the field
  • With numerous illustrations
  • Describes the present state of pediatric pharmacology and gives an overview on this fascinating field of research to colleagues from other disciplines
  • Includes supplementary material: sn.pub/extras

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 205)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 389.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 499.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 499.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (18 chapters)

  1. Front Matter

    Pages i-xii
    Download chapter PDF

  2. General Considerations and Methodological Aspects

    1. Front Matter

      Pages 1-1
      Download chapter PDF

  3. General Considerations and methodological aspects

    1. Basics and Dynamics of Neonatal and Pediatric Pharmacology

      • Hannsjörg W. Seyberth, Ralph E. Kauffman
      Pages 3-49

    2. Developmental Pharmacokinetics

      • Johannes N. van den Anker, Matthias Schwab, Gregory L. Kearns
      Pages 51-75

    3. Principles of Therapeutic Drug Monitoring

      • Wei Zhao, Evelyne Jacqz-Aigrain
      Pages 77-90

    4. Drug Delivery and Formulations

      • Jörg Breitkreutz, Joachim Boos
      Pages 91-107

  4. Development of Pediatric Medicines

    1. Front Matter

      Pages 109-109
      Download chapter PDF

  5. Development of pediatric medicines

    1. Development of Paediatric Medicines: Concepts and Principles

      • Klaus Rose, Oscar Della Pasqua
      Pages 111-124

    2. Study Design and Simulation Approach

      • Stephanie Läer, Bernd Meibohm
      Pages 125-148

    3. Efficacy Assessment in Paediatric Studies

      • Siri Wang, Pirjo Laitinen-Parkkonen
      Pages 149-168

    4. Safety Assessment in Pediatric Studies

      • Gideon Koren, Abdelbasset Elzagallaai, Fatma Etwel
      Pages 169-180

    5. Small Sample Approach, and Statistical and Epidemiological Aspects

      • Martin Offringa, Hanneke van der Lee
      Pages 181-202

    6. Sample Collection, Biobanking, and Analysis

      • Maurice J. Ahsman, Dick Tibboel, Ron A. A. Mathot, Saskia N. de Wildt
      Pages 203-217

    7. Ethical Considerations in Conducting Pediatric Research

      • Michelle Roth-Cline, Jason Gerson, Patricia Bright, Catherine S. Lee, Robert M. Nelson
      Pages 219-244

    8. Pediatric Regulatory Initiatives

      • Steven Hirschfeld, Agnes Saint-Raymond
      Pages 245-268

  6. Specific Pediatric Pharmacology

    1. Front Matter

      Pages 269-269
      Download chapter PDF

  7. Specific pediatric pharmacology

    1. Fetal Medicine and Treatment

      • Magnus Westgren
      Pages 271-283

    2. Fetal Risks of Maternal Pharmacotherapy: Identifying Signals

      • Gideon Koren
      Pages 285-294

    3. Antiepileptic Treatment in Pregnant Women: Morphological and Behavioural Effects

      • Torbjörn Tomson, Dina Battino
      Pages 295-315

    4. Preventive Medicines

      • Ulrich Heininger
      Pages 317-337
Back to top

Keywords

About this book

The objective of this volume is to give an overview of the present state of the art of pediatric clinical pharmacology including developmental physiology, pediatric-specific pathology, special tools and methods for development of drugs for children (assessment of efficacy, toxicity, long-term safety etc.) as well as regulatory and ethical knowledge and skills. In the future, structural and educational changes have to lead back to a closer cooperation and interaction of pediatrics with (clinical) pharmacology and pharmacy.

Editors and Affiliations

  • Klinik für Kinder- und Jugendmedizin, Univ.Klinikum Marburg, Marburg, Germany

    Hannsjörg W. Seyberth

  • Karolinska Institutet, Dept. Laboratory Medicine, Karolinska University Hostpital, Stockholm, Sweden

    Anders Rane

  • für Klinische Pharmakologie (IKP), Dr. Margarete Fischer-Bosch Institut, Stuttgart, Germany

    Matthias Schwab

Bibliographic Information

Publish with us

Policies and ethics

Back to top

Search

Navigation