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  • © 2004

TOR

Target of Rapamycin

Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 279)

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Table of contents (20 chapters)

  1. Front Matter

    Pages I-X
  2. TOR: The First 10 Years

    • A. Lorberg, M. N. Hall
    Pages 1-18
  3. The Role of Phosphatases in TOR Signaling in Yeast

    • K. Düvel, J. R. Broach
    Pages 19-38
  4. Yeast TOR Signaling: A Mechanism for Metabolic Regulation

    • T. Powers, I. Dilova, C.-Y. Chen, K. Wedaman
    Pages 39-51
  5. Autophagy in Yeast: ATOR-Mediated Response to Nutrient Starvation

    • Y. Kamada, T. Sekito, Y. Ohsumi
    Pages 73-84
  6. Plant Growth and the TOR Pathway

    • B. Menand, C. Meyer, C. Robaglia
    Pages 97-113
  7. TOR Action in Mammalian Cells and in Caenorhabditis elegans

    • X. Long, F. Müller, J. Avruch
    Pages 115-138
  8. mTOR Signaling to Translation

    • A.-C. Gingras, B. Raught, N. Sonenberg
    Pages 169-197
  9. Modulation of the Protein Kinase Activity of mTOR

    • J. C. Lawrence, T.-A. Lin, L. P. McMahon, K. M. Choi
    Pages 199-213
  10. Raptor and mTOR: Subunits of a Nutrient-Sensitive Complex

    • D. H. Kim, D. M. Sabatini
    Pages 259-270
  11. Kinase Activities Associated with mTOR

    • K. Yonezawa, K.-I. Yoshino, C. Tokunaga, K. Hara
    Pages 271-282
  12. mTOR: A Mediator of Intracellular Homeostasis

    • A. Jaeschke, P. B. Dennis, G. Thomas
    Pages 283-298
  13. Retroviral Oncogenes and TOR

    • M. Aoki, P. K. Vogt
    Pages 321-338

About this book

 

TOR, the Target of Rapamycin was discovered a little over ten years ago in a genetic screen in S. cerevisiae in search of mutants resistant to the cytostatic effects of the antimycotic, rapamycin. Recent studies have placed TOR at the interface between nutrient sensing and the regulation of major anbolic and catabolic responses. The editors have gathered the leading figures in the field of TOR and its role in cellular homeostasis and human diseases.

Editors and Affiliations

  • Friedrich-Miescher-Institute, Basel, Switzerland

    George Thomas

  • Whitehead Institute, Cambridge, USA

    David M. Sabatini

  • Biozentrum, University of Basel, Basel, Switzerland

    Michael N. Hall

Bibliographic Information

  • Book Title: TOR

  • Book Subtitle: Target of Rapamycin

  • Editors: George Thomas, David M. Sabatini, Michael N. Hall

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-642-18930-2

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2004

  • Hardcover ISBN: 978-3-540-00534-6Published: 25 August 2003

  • Softcover ISBN: 978-3-642-62360-8Published: 21 October 2012

  • eBook ISBN: 978-3-642-18930-2Published: 06 December 2012

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: X, 364

  • Topics: Medical Microbiology

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access