Overview
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Table of contents (25 papers)
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Front Matter
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Polycythemia Vera
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Front Matter
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Essential Thrombocythemia
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Front Matter
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Chronic Idiopathic Myelofibrosis
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Front Matter
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Keywords
About this book
Since the first description of Philadelphia chromosome-negative chronic myeloproliferative disorders more than 100 years ago, the diagnosis and therapy of these conditions have been based primarily on clinical experience and judgement. Until recently very little was known about the molecular basis of these diseases. In order to spark research in this area basic scientists and clinicians from various parts of the world have contributed to this volume, the first of its kind to put together the current knowledge. The book deals with the new WHO classification of these disorders, novel aspects of diagnostic pathology, the search for disease-relevant genes utilizing molecular biology and proteomic techniques, the description of the roles of PVR-1 and VHL genes for polycythemias and the discovery of the gene mutation responsible for the idiopathic hypereosinophilic syndrome. A chapter on anagrelide, an important novel drug for the treatment of primary thrombocythemia, is included.
Editors and Affiliations
Bibliographic Information
Book Title: Molecular Basis of Chronic Myeloproliferative Disorders
Editors: Petro E. Petrides, Heike L. Pahl
DOI: https://doi.org/10.1007/978-3-642-18738-4
Publisher: Springer Berlin, Heidelberg
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eBook Packages: Springer Book Archive
Copyright Information: Springer-Verlag Berlin Heidelberg 2004
Hardcover ISBN: 978-3-540-22485-3Published: 06 October 2004
Softcover ISBN: 978-3-642-62271-7Published: 08 October 2012
eBook ISBN: 978-3-642-18738-4Published: 06 December 2012
Edition Number: 1
Number of Pages: XII, 218
Topics: Endocrinology, Oncology, Cancer Research