Skip to main content
SpringerLink
Log in

Modelling in Molecular Biology

  • Book
  • © 2004

Overview

Editors:
  1. Gabriel Ciobanu

    1. Institute of Computer Science, Romanian Academy of Sciences, Iasi, Romania

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Grzegorz Rozenberg

    1. Institute of Advanced Computer Science, Leiden University, Leiden, The Netherlands

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • A collection of chapters presenting some possible approaches of modelling in molecular biology
  • Describes how to find regularities among empirical data, as well as conceptual models and theories
  • Includes supplementary material: sn.pub/extras

Part of the book series: Natural Computing Series (NCS)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (13 chapters)

  1. Front Matter

    Pages I-X
    Download chapter PDF

  2. Stoichiometric Foundation of Large-Scale Biochemical System Analysis

    • Daniel A. Beard, Hong Qian, James B. Bassingthwaighte
    Pages 1-19

  3. Modelling Stochastic Clonal Interference

    • Paulo RA Campos, Christoph Adami, Claus O. Wilke
    Pages 21-38

  4. Software Verification of Biomolecular Systems

    • Gabriel Ciobanu
    Pages 39-57

  5. Kinetic Modelling as a Modern Technology to Explore and Modify Living Cells

    • Oleg V. Demin, Galina V. Lebedeva, Alex G. Kolupaev, E. A. Zobova, T. Yu. Plyusnina, A. I. Lavrova et al.
    Pages 59-103

  6. Modelling Gene Assembly in Ciliates

    • Andrzej Ehrenfeucht, Tero Harju, Ion Petre, David M. Prescott, Grzegorz Rozenberg
    Pages 105-124

  7. Towards Molecular Programming — a Personal Report on DNA8 and Molecular Computing

    • Masami Hagiya
    Pages 125-140

  8. Molecular Information Theory: Solving the Mysteries of DNA

    • Sungchul Ji
    Pages 141-150

  9. Formal Modelling of C. elegans Development. A Scenario-Based Approach

    • Na’aman Kam, David Harel, Hillel Kugler, Rami Marelly, Amir Pnueli, Jane Albert Hubbard et al.
    Pages 151-173

  10. P Systems with Symport/Antiport Rules. A Survey

    • Carlos Martín-Vide, Gheorghe Păun
    Pages 175-192

  11. Mathematical Modelling of the Immune System

    • Santo Motta, Vladimir Brusic
    Pages 193-218

  12. The π-calculus as an Abstraction for Biomolecular Systems

    • Aviv Regev, Ehud Shapiro
    Pages 219-266

  13. The Topology of Evolutionary Biology

    • Bärbel M. R. Stadler, Peter F. Stadler
    Pages 267-286

  14. Models of Genome Evolution

    • Yi Zhou, Bud Mishra
    Pages 287-304

  15. Back Matter

    Pages 305-305
    Download chapter PDF
Back to top

Keywords

About this book

This volume is based on the workshop“Modelling in Molecular Biology” that tookplacein2002inSingapore. Themaingoaloftheworkshopwastopresent models/methods used in solving some fundamental problems in biosciences. The volume consists of a selection of papers presented at the workshop as well as of some other papers that are included so that the presentation of the theme of the workshop is broader and more balanced. As a matter of fact we feel that the collection of papers comprising this volume represents a wide spectrum of quite diverse ideas and trends. The paper by D. A. Beard et al. explores the common thesis that und- standingthebehaviouroflargeinteractingsystemsofmanyenzymesandre- tants underlies the modelling and simulation of whole-cell systems. Moreover, the models need to represent the basic stoichiometry, with balanced che- cal reactions and the conservation of mass, energy and charge. The authors discuss the stoichiometric and then kinetic details of approaches to modelling and simulation of biochemical systems. P. R. A. Campos et al. are concerned with models of evolution and adaptation (which is essential for precise - derstanding of molecular phylogeny). In particular, their paper is concerned with the rate of adaptation of asexual organisms(which is important because it in?uences the speed of the assumed molecular clock). It is known that for such organisms the rate of adaptation does not steadily increase with the - creasing rate of advantageous mutations, and this paper studies the mutual interference of two advantageous mutants that are each initially present in only a single organism.

Editors and Affiliations

  • Institute of Computer Science, Romanian Academy of Sciences, Iasi, Romania

    Gabriel Ciobanu

  • Institute of Advanced Computer Science, Leiden University, Leiden, The Netherlands

    Grzegorz Rozenberg

About the editors

G. Ciobanu is Professor at the Romanian Academy, Institute of Computer Science and has received the first "Grigore Moisil" award for theoretical computer science offered by the Romanian Academy. Over 60 papers published in international journals.

G. Rozenberg is multiple Springer author and editor of books and series (EATCS, NCS).

Bibliographic Information

Publish with us

Policies and ethics

Back to top

Search

Navigation