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Chemistry of Opioids

  • Book
  • © 2011

Overview

Editors:
  1. Hiroshi Nagase

    1. School of Pharmaceutical Sciences, Dept. Medicinal Chemistry, Kitasato University, Tokyo, Japan

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  • This series presents critical reviews of the present position and future trends in modern chemical research
  • Short and concise reports on chemistry, each written by the world renowned experts
  • Still valid and useful after 5 or 10 years
  • More information as well as the electronic version of the whole content available at: springerlink.com
  • Includes supplementary material: sn.pub/extras

Part of the book series: Topics in Current Chemistry (TOPCURRCHEM, volume 299)

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Table of contents (9 chapters)

  1. Front Matter

    Pages i-xiii
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  2. Recent Advances in the Synthesis of Morphine and Related Alkaloids

    • Noritaka Chida
    Pages 1-28

  3. Opioids in Preclinical and Clinical Trials

    • Hiroshi Nagase, Hideaki Fujii
    Pages 29-62

  4. Synthesis of 14-Alkoxymorphinan Derivatives and Their Pharmacological Actions

    • Helmut Schmidhammer, Mariana Spetea
    Pages 63-91

  5. 14-Amino-4,5-Epoxymorphinan Derivatives and Their Pharmacological Actions

    • John W. Lewis, Stephen M. Husbands
    Pages 93-119

  6. Nonpeptidic Delta (δ) Opioid Agonists and Antagonists of the Diarylmethylpiperazine Class: What Have We Learned?

    • Silvia N. Calderon
    Pages 121-140

  7. Synthesis of Neoclerodane Diterpenes and Their Pharmacological Effects

    • Kimberly M. Lovell, Katherine M. Prevatt-Smith, Anthony Lozama, Thomas E. Prisinzano
    Pages 141-185

  8. Synthesis of Novel Basic Skeletons Derived from Naltrexone

    • Hiroshi Nagase, Hideaki Fujii
    Pages 187-237

  9. Twin and Triplet Drugs in Opioid Research

    • Hideaki Fujii
    Pages 239-275

  10. 3D-Pharmacophore Identification for κ-Opioid Agonists Using Ligand-Based Drug-Design Techniques

    • Noriyuki Yamaotsu, Shuichi Hirono
    Pages 277-307

  11. Back Matter

    Pages 309-312
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Keywords

About this book

Recent Advances in the Synthesis of Morphine and Related Alkaloids; by N. Chida * Opioids in Preclinical and Clinical Trials; by H. Nagase and H. Fujii * Synthesis of 14-Alkoxymorphinan Derivatives and Their Pharmacological Actions; by H. Schmidhammer and M. Spetea * 14-Amino-4,5-Epoxymorphinan Derivatives and Their Pharmacological Actions; by J. W. Lewis and S. M. Husbands * Nonpeptidic Delta (δ) Opioid Agonists and Antagonists of the Diarylmethylpiperazine Class: What Have We Learned?; by S. N. Calderon * Synthesis of Neoclerodane Diterpenes and Their Pharmacological Effects; by K. M. Lovell, K. M. Prevatt-Smith, A. Lozama and T. E. Prisinzano * Synthesis of Novel Basic Skeletons Derived from Naltrexone; by H. Nagase and H. Fujii * Twin and Triplet Drugs in Opioid Research; by H. Fujii *  3D-Pharmacophore Identification for κ-Opioid Agonists Using Ligand-Based Drug-Design Techniques; by N. Yamaotsu and S. Hirono

Editors and Affiliations

  • School of Pharmaceutical Sciences, Dept. Medicinal Chemistry, Kitasato University, Tokyo, Japan

    Hiroshi Nagase

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