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Epigenetics and Human Reproduction

  • Book
  • © 2011

Overview

Editors:
  1. Sophie Rousseaux

    1. INSERM U309, Labo. Biologie Moléculaire et, Institut Albert Bonniot, La Tronche CX, France

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  2. Saadi Khochbin

    1. INSERM U309, Labo. Biologie Moléculaire et, Institut Albert Bonniot, La Tronche CX, France

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  • Epigenetics is a rapidly expanding field in medical and biological research which concerns heritable traits that are not attributable to changes in the DNA sequence Epigenetic mechanisms play key roles in many biological processes, and it has become clear that their disruption can gives rise to diverse pathologies in humans
  • Includes supplementary material: sn.pub/extras

Part of the book series: Epigenetics and Human Health (EHH)

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Table of contents (15 chapters)

  1. Front Matter

    Pages i-xvi
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  2. Medical Aspects and Questions Raised on the Molecular Basis of Epigenome Involvement in Reproduction

    1. Front Matter

      Pages 1-1
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    2. Potential Epigenetic Consequences Associated with Assisted Reproduction

      • Amanda Fortier, Jacquetta Trasler
      Pages 3-18

    3. Germ Cell Cancer, Testicular Dysgenesis Syndrome and Epigenetics

      • Kristian Almstrup, Olga Mlynarska, Ewa Rajpert-De Meyts
      Pages 19-44

    4. Medical Implications of Sperm Nuclear Quality

      • Rafael Oliva, Sara de Mateo
      Pages 45-83

    5. Gene Expression/Phenotypic Abnormalities in Placental Tissues of Sheep Clones: Insurmountable Block in Cloning Progress?

      • Pasqualino Loi, Grazyna Ptak
      Pages 85-96

  3. Fundamental Aspects of Genome and Epigenome Reprogramming During Gametogenesis

    1. Front Matter

      Pages 97-97
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    2. Epigenetic Reprogramming Associated with Primordial Germ Cell Development

      • Yoshiyuki Seki
      Pages 99-117

    3. Epigenetic Factors and Regulation of Meiotic Recombination in Mammals

      • P. Barthès, J. Buard, B. de Massy
      Pages 119-156

    4. Meiotic Pairing of Homologous Chromosomes and Silencing of Heterologous Regions

      • Sam Schoenmakers, Willy M. Baarends
      Pages 157-186

    5. Histone Variants during Gametogenesis and Early Development

      • P. de Boer, M. de Vries, S. Gochhait
      Pages 187-212

    6. Genome Organization by Vertebrate Sperm Nuclear Basic Proteins (SNBPs)

      • Juan Ausió, Laurence R. Brewer, Lindsay Frehlick
      Pages 213-230

    7. Epigenetics in Male Reproduction: A Practical Introduction to the Informatics of Next Generation Sequencing

      • Adrian E. Platts, Claudia Lalancette, Stephen A. Krawetz
      Pages 231-258

  4. Re-organization of Nuclear Compartments During Gametogenesis

    1. Front Matter

      Pages 259-259
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    2. Organization of Chromosomes During Spermatogenesis and in Mature Sperm

      • Olga Mudrak, Irina Zalenskaya, Andrei Zalensky
      Pages 261-277

    3. Nuclear Lamins in Mammalian Spermatogenesis

      • Manfred Alsheimer, Daniel Jahn, Sabine Schramm, Ricardo Benavente
      Pages 279-288

  5. Fundamental Aspects of Gene Expression Regulation During Gametogenesis

    1. Front Matter

      Pages 289-289
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    2. Specific Transcription Regulatory Mechanisms of Male Germ Cells

      • Irwin Davidson
      Pages 291-309

    3. The Chromatoid Body: A Specialized RNA Granule of Male Germ Cells

      • Ippei Nagamori, Adam Cruickshank, Paolo Sassone-Corsi
      Pages 311-328

    4. Sperm RNA: Reading the Hidden Message

      • David Miller
      Pages 329-353
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Keywords

About this book

Epigenetics is a rapidly expanding field in medical and biological research which concerns heritable traits that are not attributable to changes in the DNA sequence. Epigenetic mechanisms play key roles in many biological processes, and it has become clear that their disruption can gives rise to diverse pathologies in humans. Edited by preeminent experts, Sophie Rousseaux and Saadi Khochbin, this volume in the ‘Epigenetics and Human Health’ series discusses the role of epigenetics in human reproduction

Editors and Affiliations

  • INSERM U309, Labo. Biologie Moléculaire et, Institut Albert Bonniot, La Tronche CX, France

    Sophie Rousseaux, Saadi Khochbin

Bibliographic Information

  • Book Title: Epigenetics and Human Reproduction

  • Editors: Sophie Rousseaux, Saadi Khochbin

  • Series Title: Epigenetics and Human Health

  • DOI: https://doi.org/10.1007/978-3-642-14773-9

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2011

  • Hardcover ISBN: 978-3-642-14772-2Published: 05 November 2010

  • Softcover ISBN: 978-3-642-26582-2Published: 02 January 2013

  • eBook ISBN: 978-3-642-14773-9Published: 03 November 2010

  • Series ISSN: 2191-2262

  • Series E-ISSN: 2191-2270

  • Edition Number: 1

  • Number of Pages: XVI, 372

  • Topics: Human Genetics, Reproductive Medicine

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