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Pathogenicity Islands and the Evolution of Pathogenic Microbes

Volume I

  • Book
  • © 2002

Overview

Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 264/1)

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Table of contents (11 chapters)

Keywords

About this book

It has been known for a number of years that not only pathogenicity islands but also plasmids and bacteriophages are able to carry genes whose products are involved in pathogenic processes. Accordingly, such elements and their products play an important role in pathogenesis due to the intestinal E. coli as well due to Shigellae. Another interesting aspect which is reflected in different articles is that genomes evolve by acquisition of new pieces of DNA following gene transfer, but also by genome reduction. Different mechanisms include the deletion of sequences or the elimination of functions by the accumulation of point mutations or rearrangements.

Reviews

From the reviews:

"In addition to classic mutational events, a highly successful strategy of generating genetic diversity in bacteria is the acquisition of genomic islands. … This compendium … features an international assembly of authors including W. Arber (Basel) giving a lucid introduction into the evolution of prokaryotic genomes. The two-volume work provides a comprehensive overview of the current state of knowledge on PAIs and other mobile virulence determinants in bacterial as well as fungal pathogens of humans and plants." (Susanne Rohrer, BioWorld, Issue 6, 2002)

Editors and Affiliations

  • Institut für Molekulare Infektionsbiologie, Universität Würzburg, Würzburg, Germany

    Jörg Hacker

  • Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, USA

    James B. Kaper

Bibliographic Information

  • Book Title: Pathogenicity Islands and the Evolution of Pathogenic Microbes

  • Book Subtitle: Volume I

  • Editors: Jörg Hacker, James B. Kaper

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-662-09217-0

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2002

  • Hardcover ISBN: 978-3-540-42681-3Published: 01 March 2002

  • Softcover ISBN: 978-3-642-07656-5Published: 01 December 2010

  • eBook ISBN: 978-3-662-09217-0Published: 09 March 2013

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: XVII, 234

  • Number of Illustrations: 23 b/w illustrations

  • Topics: Microbiology, Human Genetics

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