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Protective and Pathological Immune Responses in the CNS

  • Book
  • © 2002

Overview

Editors:
  1. Bernhard Dietzschold

    1. Department of Microbiology and Immunology, Thomas Jefferson University Philadelphia, Philadelphia, USA

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  2. Jürgen A. Richt

    1. USDA-ARS-National Animal Disease Center, Ames, USA
      Institute of Virology, Justus-Liebig-Universität Giessen, Giessen, Germany

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 265)

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Table of contents (13 chapters)

  1. Front Matter

    Pages I-IX
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  2. Hierarchy of Immune Responses to Antigen in the Normal Brain

    • C. J. Harling-Berg, J. J. Hallett, J. T. Park, P. M. Knopf
    Pages 1-22

  3. Cytokines and Chemokines as Mediators of Protection and Injury in the Central Nervous System Assessed in Transgenic Mice

    • J. Wang, V. C. Asensio, I. L. Campbell
    Pages 23-48

  4. Cytokines in Degenerative Brain Diseases: Lessons from Transgenic Animals

    • U. L. M. Eisel
    Pages 49-62

  5. Innate Immune Responses in Viral Encephalitis

    • C. S. Reiss, D. A. Chesler, J. Hodges, D. D. C. Ireland, N. Chen
    Pages 63-94

  6. Apoptosis in Viral Infections of Neurons: a Protective or Pathologic Host Response?

    • B. Levine
    Pages 95-118

  7. Markers of Central Nervous System Glia and Neurons In Vivo During Normal and Pathological Conditions

    • J. M. Redwine, C. F. Evans
    Pages 119-140

  8. The Role of T Cells in Brain Pathology

    • M. Bradl, A. Flügel
    Pages 141-162

  9. Immunopathology and Immunoprotection in CNS Virus Infections: Mechanisms of Virus Clearance from the CNS

    • D. C. Hooper, C. Sauder, G. S. Scott, B. Dietzschold, J. A. Richt
    Pages 163-182

  10. HIV-1 and the Central Nervous System

    • M. Tardieu, A. Boutet
    Pages 183-195

  11. HTLV-1-Mediated Immunopathological CNS Disease

    • B. Kitze, K. Usuku
    Pages 197-211

  12. Listeria monocytogenes: a Model System to Study Invasion and Spread of Bacteria in the Central Nervous System

    • E. Domann, M. Deckert, D. Schlüter, T. Chakraborty
    Pages 213-226

  13. Parasites and the Brain: Neuroinvasion, Immunopathogenesis and Neuronal Dysfunctions

    • K. Kristensson, J. D. M. Mhlanga, M. Bentivoglio
    Pages 227-257

  14. Immune Responses in Glioblastoma: an Avenue to Effective Cancer Therapy or a Mere Epiphenomenon?

    • H. J. Schluesener, R. Meyermann, M. Deininger
    Pages 259-267

  15. Back Matter

    Pages 269-280
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Keywords

About this book

In spite of the protection of the CNS there are situations where immune responses occur due to different disease processes. While antigen-specific cells of the adaptive immune response are not normally functional in the CNS tissue, CNS resident cells respond to infection or insult. One mechanisms is through the induction of apoptosis in virus infected neurons, which may be protective or pathogenic depending on the extent of cell death.

Editors and Affiliations

  • Department of Microbiology and Immunology, Thomas Jefferson University Philadelphia, Philadelphia, USA

    Bernhard Dietzschold

  • USDA-ARS-National Animal Disease Center, Ames, USA

    Jürgen A. Richt

  • Institute of Virology, Justus-Liebig-Universität Giessen, Giessen, Germany

    Jürgen A. Richt

Bibliographic Information

  • Book Title: Protective and Pathological Immune Responses in the CNS

  • Editors: Bernhard Dietzschold, Jürgen A. Richt

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-662-09525-6

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2002

  • Hardcover ISBN: 978-3-540-42668-4Published: 01 March 2002

  • Softcover ISBN: 978-3-642-07655-8Published: 01 December 2010

  • eBook ISBN: 978-3-662-09525-6Published: 11 November 2013

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: IX, 280

  • Number of Illustrations: 51 b/w illustrations, 4 illustrations in colour

  • Topics: Immunology, Neurosciences

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