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Visualizing Immunity

  • Book
  • © 2009

Overview

Editors:
  1. Michael Dustin
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    You can also search for this editor in PubMed   Google Scholar

  2. Dorian McGavern
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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 334)

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-xii
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  2. Two-Photon Imaging of the Immune System: A Custom Technology Platform for High-Speed, Multicolor Tissue Imaging of Immune Responses

    • Andrew Bullen, Rachel S. Friedman, Matthew F. Krummel
    Pages 1-29

  3. Visualizing Intermolecular Interactions in T Cells

    • Nicholas R.J. Gascoigne, Jeanette Ampudia, Jean-Pierre Clamme, Guo Fu, Carina Lotz, Michel Mallaun et al.
    Pages 31-46

  4. Multiscale analysis of T cell activation: correlating in vitro and in vivo analysis of the immunological synapse

    • Michael L. Dustin
    Pages 47-70

  5. T Cell Migration Dynamics Within Lymph Nodes During Steady State: An Overview of Extracellular and Intracellular Factors Influencing the Basal Intranodal T Cell Motility

    • Tim Worbs, Reinhold Förster
    Pages 71-105

  6. Chemoattract Receptor Signaling and Its Role in Lymphocyte Motility and Trafficking

    • John H. Kehrl, Il-Young Hwang, Chung Park
    Pages 107-127

  7. New Insights Into Leukocyte Recruitment by Intravital Microscopy

    • Alexander Zarbock, Klaus Ley
    Pages 129-152

  8. Visualizing the Molecular and Cellular Events Underlying the Initiation of B-Cell Activation

    • Naomi E. Harwood, Facundo D. Batista
    Pages 153-177

  9. Tracking the Dynamics of Salmonella Specific T Cell Responses

    • James J. Moon, Stephen J. McSorley
    Pages 179-198

  10. Imaging Listeria monocytogenes Infection In Vivo

    • Vjollca Konjufca, Mark J. Miller
    Pages 199-226

  11. Inflammation on the Mind: Visualizing Immunity in the Central Nervous System

    • Silvia S. Kang, Dorian B. McGavern
    Pages 227-263

  12. Multiphoton Imaging of Cytotoxic T Lymphocyte-Mediated Antitumor Immune Responses

    • Alexandre Boissonnas, Alix Scholer-Dahire, Luc Fetler, Sebastian Amigorena
    Pages 265-287

  13. Back Matter

    Pages 289-292
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Keywords

About this book

Researchers have used a variety of techniques over the past century to gain fun- mental insights in the field of immunology and, as technology has advanced, so too has the ability of researchers to delve deeper into the biological mechanics of immunity. The immune system is exceedingly complex and must patrol the entire body to protect us from foreign invaders. This requires the immune system to be highly mobile and adaptable - able to respond to diverse microbial challenges while maintaining the ability to distinguish self from a foreign invader. This latter feature is of great importance because the immune system is equipped with toxic mediators, and a failure in self/non-self discrimination can result in serious diseases. Fortunately, in most cases, the immune system operates within the framework of its elegant design and protects us from diverse microbial challenges without initiating disease. Because the immune system is not confined to a single tissue, a comprehensive understanding of immunity requires that research be conducted at the molecular, cellular, and systems level. Immune cells often find customized solutions to h- dling microbial insults that depend on the tissue(s) in which the pathogen is found.

Bibliographic Information

  • Book Title: Visualizing Immunity

  • Editors: Michael Dustin, Dorian McGavern

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-540-93864-4

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2009

  • Hardcover ISBN: 978-3-540-93862-0Published: 25 May 2009

  • Softcover ISBN: 978-3-642-10101-4Published: 19 October 2010

  • eBook ISBN: 978-3-540-93864-4Published: 12 June 2009

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: XII, 292

  • Number of Illustrations: 6 b/w illustrations, 25 illustrations in colour

  • Topics: Immunology, Human Physiology, Molecular Medicine

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