Editors:
- In each volume an overview chapter introduces the newcomer to the topic covered
- Series covers hot topics of frontier research summarized by reputed scientists in the field
- Review series is topic related
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Part of the book series: Topics in Medicinal Chemistry (TMC, volume 3)
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Table of contents (6 chapters)
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Front Matter
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Back Matter
About this book
Ion channels play a vital role in basic physiological functions such as generation of electrical activity in nerves and muscle, control of cardiac excitability, intracellular signaling, hormone secretion, cell proliferation and many other biological processes. Because of their prevalence and the critical role they play in virtually all tissue types and organs, ion channels are also involved in a number of pathophysiological conditions. The aim of this volume is to review recent advances in the field of ion channel related diseases. Following an overview chapter summarizing the current state of ion channel screening technologies, five topics covering areas such as cancer, cardiac arrhythmias, cystic fibrosis, and pain have been selected, and the current state of knowledge is presented by leading experts in their field. Each chapter is structured to cover the biological rationale for the target, the current status in the development of agents to treat the disease, and future prospects and challenges facing each therapeutic area. The reader will receive a critical overview covering the progress made in the rapidly developing and complex field of ion channels and diseases.
Bibliographic Information
Book Title: Ion Channels
Editors: Bernard Fermini, Birgit T. Priest
Series Title: Topics in Medicinal Chemistry
DOI: https://doi.org/10.1007/978-3-540-79729-6
Publisher: Springer Berlin, Heidelberg
eBook Packages: Chemistry and Materials Science, Chemistry and Material Science (R0)
Copyright Information: Springer-Verlag Berlin Heidelberg 2008
Hardcover ISBN: 978-3-540-79728-9Published: 23 July 2008
Softcover ISBN: 978-3-642-09855-0Published: 17 November 2010
eBook ISBN: 978-3-540-79729-6Published: 04 September 2008
Series ISSN: 1862-2461
Series E-ISSN: 1862-247X
Edition Number: 1
Number of Pages: XIV, 171
Number of Illustrations: 33 b/w illustrations, 10 illustrations in colour
Topics: Medicinal Chemistry, Pharmacology/Toxicology, Organic Chemistry, Molecular Medicine