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  • © 2009

Antiviral Strategies

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 189)

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-xi
  2. Antiviral Strategies

    • B. Müller, Hans-Georg Kräusslich
    Pages 1-24
  3. Approaches for the Development of Antiviral Compounds: The Case of Hepatitis C Virus

    • Raymond F. Schinazi, Steven J. Coats, Leda C. Bassit, Johan Lennerstrand, James H. Nettles, Selwyn J. Hurwitz
    Pages 25-51
  4. Antiviral Agents Acting as DNA or RNA Chain Terminators

    • E. De Clercq, J. Neyts
    Pages 53-84
  5. Viral Protease Inhibitors

    • Jeffrey Anderson, Celia Schiffer, Sook-Kyung Lee, Ronald Swanstrom
    Pages 85-110
  6. Anti-Influenza Drugs: The Development of Sialidase Inhibitors

    • Mark von Itzstein, Robin Thomson
    Pages 111-154
  7. Other Inhibitors of Viral Enzymes and Functions

    • H. Zimmermann, G. Hewlett, H. Rübsamen-Waigmann
    Pages 155-176
  8. Inhibitors of Viral Entry

    • Tom Melby, Mike Westby
    Pages 177-202
  9. Interferons and Their Use in Persistent Viral Infections

    • Stéphane Chevaliez, Jean-Michel Pawlotsky
    Pages 203-241
  10. Antiviral Gene Therapy

    • D. Laer, C. Baum, U. Protzer
    Pages 265-297
  11. Socio-Economic Impact of Antiviral Intervention

    • S. Fleßa, P. Marschall
    Pages 347-374
  12. Back Matter

    Pages 375-379

About this book

A crucial issue for antiviral therapy is the fact that all antiviral substances rapidly select for resistance; thus, monitoring and overcoming resistance has become a most important clinical paradigm of antiviral therapy. This calls for cautious use of antiviral drugs and implementation of combination therapies. In parallel, efforts in drug discovery have to be continued to develop compounds with novel mode-of-action and activity against resistant strains. This book reviews the current status of antiviral therapy, from the roads to development of new compounds to their clinical use and cost effectiveness. Individual chapters address in more detail all available drug classes and outline new approaches currently under development.

Editors and Affiliations

  • Hygiene Institute Department of Virology, Universitätsklinikum Heidelberg, Heidelberg, Germany

    Hans-Georg Kräusslich, Ralf Bartenschlager

Bibliographic Information

Buy it now

Buying options

eBook USD 259.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 329.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access