Sepsis

Sepsis is an important public health problem around the world. Severe sepsis carries significant morbidity, mortality and high costs. The incidence of sepsis is increasing because of the aging population, the growing number of immunocompromised hosts, the increasing use of invasive procedures, and, to a lesser extent, antibiotic resistance among pathogens. Despite recent advances in the pathogenesis, diagnosis, and therapeutic approaches the mortality rate associated with this condition remains high. Therefore, the goal of Sepsis: New Strategies is to review novel targets to be considered in patients with severe sepsis and to assess new developments for patients with sepsis originating in the respiratory tract.

• Antimicrobial therapy
• Immunomodulation
• Inflammation
• Pneumonia
• Sepsis
• antibiotic use
• antibiotics
• infectious diseases

From the reviews:

"This brief monograph reviews immunomodulatory and anti-inflammatory strategies under investigation as adjuncts in management of sepsis and pneumonia. … Practitioners with an academic interest in sepsis are an appropriate audience for this work … . Chapters are clearly written and tables and line drawings have good pedagogic quality." (David J. Dries, Doody’s Review Services, January, 2009)

• Critical Care Department – Joan XXIII University Hospital, Universidad Rovira & Virgili and Institut Pere Virgili CIBER Enfermedades Respiratorias, Tarragona, Spain

  Jordi Rello

• Division Pulmonary and Critical Care Medicine, San Antonio, USA

  Marcos I. Restrepo

• Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, USA

  Marcos I. Restrepo

• South Texas Veterans Health Care System Audie L. Murphy Division, Veterans Evidence-Based Research Dissemination Implementation Center (VERDICT), San Antonio, USA

  Marcos I. Restrepo

Policies and ethics