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RNA Technologies in Cardiovascular Medicine and Research

  • Book
  • © 2008

Overview

Editors:
  1. Volker A. Erdmann

    1. Institute for Chemistry/Biochemistry, Free University of Berlin, Berlin, Germany

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  2. Wolfgang Poller

    1. Clinic for Cardiology and Pneumology Campus Benjamin Franklin, Charite University Medicine Berlin, Berlin, Germany

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  3. Jan Barciszewski

    1. Institute of Bioorganic Chemistry of the Polish Academy of Sciences, Poznan, Poland

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  • Currently no comprehensive overview on potential and challenges of RNAi and other RNA technologies for basic cardiovascular biology and for the clinical management of patients with cardiovascular disorders

  • Book will be comprehensive in that it does not only treat the phenomenon of RNAi in all its facets (as most recently published books), but does explicitly cover the many other aspects of the “RNA World” (pathogenic and therapeutic potential of microRNAs, aptamer technology, etc.), too

  • With this significantly broadened scope as compared to currently existing books it appears to be an urgently needed new publication

  • Includes supplementary material: sn.pub/extras

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-xiv
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  2. MicroRNA

    1. An Overview of MicroRNA

      • E. Wang
      Pages 3-15

    2. MicroRNAs and Their Potential

      • M. Abdellatif
      Pages 17-34

    3. miRNAs and Their Emerging Role in Cardiac Hypertrophy

      • T. E. Callis, M. Tatsuguchi, D. Z. Wang
      Pages 35-52

    4. MicroRNAs and the Control of Heart Pathophysiology

      • D. Catalucci, M. V. G. Latronico, G. Condorelli
      Pages 53-68

    5. MicroRNA Systems Biology

      • E. Wang
      Pages 69-86

  5. Noncoding, Aptamer and Antisense RNAs

    1. Noncoding RNAs in Human Diseases

      • M. Szymański, J. Barciszewski
      Pages 235-254

    2. Aptamers and siRNAs in Cardiovascular Disease

      • C. M. Blake, S. Oney, S. M. Nimjee, B. A. Sullenger
      Pages 255-287

    3. Nucleic Acid Aptamers for Cardiovascular Therapeutics

      • P. S. Pendergrast, K. M. Thompson, R. G. Schaub
      Pages 289-297

    4. NFκB Decoy Oligodeoxynucleotide-Based Therapy in Cardiovascular Diseases

      • H. Nakagami, M. K. Osako, N. Tomita, R. Morishita
      Pages 299-309

    5. Antisense Therapy for Restenosis Following Percutaneous Coronary Interventions

      • N. Kipshidze
      Pages 311-324

    6. Toxic RNA in Pathogenesis of Human Neuromuscular Disorders

      • D. Napierala, M. Napierala
      Pages 325-353

  6. Back Matter

    Pages 355-358
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Keywords

About this book

In this book the authors review the field and explore the potential role of RNAi and other RNA technologies in cardiovascular medicine and research. They highlight the impressive recent progress but also the hurdles that still must be overcome before this promising technology is finally ready for translation and clinical use.

Editors and Affiliations

  • Institute for Chemistry/Biochemistry, Free University of Berlin, Berlin, Germany

    Volker A. Erdmann

  • Clinic for Cardiology and Pneumology Campus Benjamin Franklin, Charite University Medicine Berlin, Berlin, Germany

    Wolfgang Poller

  • Institute of Bioorganic Chemistry of the Polish Academy of Sciences, Poznan, Poland

    Jan Barciszewski

Bibliographic Information

  • Book Title: RNA Technologies in Cardiovascular Medicine and Research

  • Editors: Volker A. Erdmann, Wolfgang Poller, Jan Barciszewski

  • DOI: https://doi.org/10.1007/978-3-540-78709-9

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2008

  • Hardcover ISBN: 978-3-540-78708-2Published: 09 July 2008

  • Softcover ISBN: 978-3-642-09746-1Published: 19 October 2010

  • eBook ISBN: 978-3-540-78709-9Published: 16 July 2008

  • Edition Number: 1

  • Number of Pages: XIV, 358

  • Number of Illustrations: 55 b/w illustrations

  • Topics: Molecular Medicine, Human Genetics, Biochemistry, general

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