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  • © 2007

Metabolomics

A Powerful Tool in Systems Biology

  • Gives a fresh substantial and in-depth overview on metabolomics
  • Addresses all major challenges of the field
  • Offers real strategies for understanding cellular complexity
  • Includes supplementary material: sn.pub/extras

Part of the book series: Topics in Current Genetics (TCG, volume 18)

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Table of contents (10 chapters)

  1. Front Matter

    Pages I-XVI
  2. The role of metabolomics in systems biology

    • Jens Nielsen, Michael C. Jewett
    Pages 1-10
  3. Analytical methods from the perspective of method standardization

    • Silas G. Villas-Bôas, Albert Koulman, Geoffrey A. Lane
    Pages 11-52
  4. Analytical methods from the perspective of method standardization

    • Silas G. Villas-Bôas, Albert Koulman, Geoffrey A. Lane
    Pages 487-513
  5. Reporting standards

    • Nigel Hardy, Helen Jenkins
    Pages 53-73
  6. The Golm Metabolome Database: a database for GC-MS based metabolite profiling

    • Jan Hummel, Joachim Selbig, Dirk Walther, Joachim Kopka
    Pages 75-95
  7. Reconstruction of dynamic network models from metabolite measurements

    • Matthias Reuss, Luciano Aguilera-Vázquez, Klaus Mauch
    Pages 97-127
  8. E. coli metabolomics: capturing the complexity of a “simple” model

    • Martin Robert, Tomoyoshi Soga, Masaru Tomita
    Pages 189-234
  9. The exo-metabolome in filamentous fungi

    • Ulf Thrane, Birgitte Anderson, Jens C. Frisvad, Jørn Smedsgaard
    Pages 235-252
  10. The importance of anatomy and physiology in plant metabolomics

    • Ute Roessner, Filomena Pettolino
    Pages 253-278
  11. Back Matter

    Pages 279-284

About this book

The metabolome comprises the complete set of metabolites, the non-genetically encoded substrates, intermediates, and products of metabolic pathways, associated with a cell. Given the increasing demand to quantitatively identify the metabolome and understand how trafficking of metabolites through the metabolic network impact cellular behavior, metabolomics has emerged as an important complementary technology to the cell-wide measurements of mRNA, proteins, fluxes, and interactions (e.g., protein-DNA). Metabolomics is already a powerful tool in drug discovery and development and in metabolic engineering. While maintaining these strengths, the field promises to play a heightened role in systems biology research, which is transforming the practice of medicine and our ability to engineer living organisms.

This book brings together the latest results in the field of metabolomics. It comprehensively presents the current state of the metabolomics field by underscoring experimental methods, analysis techniques, standardization practices, and advances in specific model systems. As a result, it significantly broadens our perspective on the principles and strategies underpinning this emerging field.

Bibliographic Information

Buy it now

Buying options

eBook USD 219.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 279.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 279.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access