Skip to main content
SpringerLink
Log in

Viruses and Apoptosis

  • Book
  • © 2004

Overview

Editors:
  1. Covadonga Alonso

    1. Dpt. Biotechnologia, INIA, Madrid, Spain

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Latest book to describe molecular pathways controlled by viral genes and the new perspectives this knowledge opens for gene and cancer therapy
  • Includes supplementary material: sn.pub/extras

Part of the book series: Progress in Molecular and Subcellular Biology (PMSB, volume 36)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 16.99 USD 84.99
Discount applied Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (15 chapters)

  1. Front Matter

    Pages I-XVI
    Download chapter PDF

  2. Cell Death Suppressors Encoded by Cytomegalovirus

    • V. S. Goldmacher
    Pages 1-18

  3. Apoptosis Regulator Genes Encoded by Poxviruses

    • M. Barry, S. T. Wasilenko, T. L. Stewart, J. M. Taylor
    Pages 19-37

  4. T-Cell-Mediated Control of Poxvirus Infection in Mice

    • A. Müllbacher, R. V. Blanden
    Pages 39-55

  5. Switching on and Off the Cell Death Cascade: African Swine Fever Virus Apoptosis Regulation

    • B. Hernáez, J. M. Escribano, C. Alonso
    Pages 57-69

  6. Neuronal Apoptosis Pathways in Sindbis Virus Encephalitis

    • Pablo M. Irusta, J. Marie Hardwick
    Pages 71-93

  7. Apoptotic Pathways Triggered By HIV and Consequences on T Cell Homeostasis and HIV-Specific Immunity

    • M.-L. Gougeon
    Pages 95-115

  8. HIV and Apoptosis: a Complex Interaction Between Cell Death and Virus Survival

    • M. Bermejo, J. Alcamí, J. Gil
    Pages 117-149

  9. Poliovirus and Apoptosis

    • B. Blondel, T. Couderc, Y. Simonin, A.-S. Gosselin, F. Guivel-Benhassine
    Pages 151-169

  10. Flaviviruses and Apoptosis Regulation

    • A. Cetteau, M.-P. Courageot, P. Desprès
    Pages 171-189

  11. Manipulation of Apoptosis by Herpes Viruses (Kaposi’s Sarcoma Pathogenesis)

    • P. Feng, C. Scott, S.-H. Lee, N.-H. Cho, J. U. Jung
    Pages 191-205

  12. Exploitation of Cell Cycle and Cell Death Controls by Adenoviruses: The Road to a Productive Infection

    • I. Alasdair Russell, J. A. Royds, A. W. Braithwaite
    Pages 207-243

  13. Induction of Transformed Cell-Specific Apoptosis by the Adenovirus E4orf4 Protein

    • T. Kleinberger
    Pages 245-267

  14. Epstein-Barr Virus Signal Transduction and B-Lymphocyte Growth Transformation

    • K. M. Izumi
    Pages 269-288

  15. SV40 and Notch-I: Multi-functionality Meets Pleiotropy

    • M. Carbone, M. Bocchetta
    Pages 289-305

  16. Signal Transduction and Apoptosis Pathways as Therapeutic Targets

    • P. F. Valerón, S. Aznar-Benitah, J. C. Lacal
    Pages 307-323

  17. Back Matter

    Pages 325-342
    Download chapter PDF
Back to top

Keywords

About this book

The pathogenesis of viral infections involves dynamic interactions between viruses and hosts,which can result in different outcomes including cell death, elimination of the virus or latent infection.Viruses deliver genomes and p- teins with signaling potential into target cells, resulting in growth, prolife- tion and apoptosis.Viral infection modi?es key cell regulatory elements involved in apoptotic pathways to successfully accomplish viral replication despite the toxicity of viral products and the immune response elicited against the virus.Also,the interplay between virus-induced apoptosis and cell survival is mediated by an accurate balance between pro-death and anti-apoptotic signals triggered by cellular and viral proteins.Hence,viral survival products causing a delay in the completion of apoptotic process can be critical in the replication and propagation of viruses. Viral control of apoptosis can be a double-edged sword.In some viral inf- tions, immune cell apoptosis will contribute to pathogenesis and determine disease evolution either by direct infection of immune cells or as a result of bystander cell apoptosis caused by viral proteins or mediators secreted from infected cells. The apoptotic mechanisms contributing to HIV pathogenesis, the functional consequences on the immune system and the effect of antiviral therapies on this process will be reviewed in depth in this Volume.

Editors and Affiliations

  • Dpt. Biotechnologia, INIA, Madrid, Spain

    Covadonga Alonso

Bibliographic Information

  • Book Title: Viruses and Apoptosis

  • Editors: Covadonga Alonso

  • Series Title: Progress in Molecular and Subcellular Biology

  • DOI: https://doi.org/10.1007/978-3-540-74264-7

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2004

  • Softcover ISBN: 978-3-540-74263-0Published: 07 December 2007

  • eBook ISBN: 978-3-540-74264-7Published: 18 April 2013

  • Series ISSN: 0079-6484

  • Series E-ISSN: 2197-8484

  • Edition Number: 1

  • Number of Pages: XVI, 342

  • Number of Illustrations: 16 b/w illustrations

  • Topics: Cell Biology, Cancer Research, Biochemistry, general

Publish with us

Policies and ethics

Back to top

Search

Navigation