Editors:
- Describes state-of-the-art concepts and methods (including their applications), for the first time covered in book form
- Shows the broad range of methodologies developed in the field, from DNA shuffling and domain swapping to protein splicing, protein modification and unnatural amino acid mutagenesis via genetic code expansion
- Includes supplementary material: sn.pub/extras
Part of the book series: Nucleic Acids and Molecular Biology (NUCLEIC, volume 22)
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Table of contents (12 chapters)
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Front Matter
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Back Matter
About this book
Site-specific mutagenesis of DNA, developed some thirty years ago, has proven to be one of the most important advances in biology. By allowing the site-specific replacement of any amino acid in a protein with one of the other nineteen amino acids, it ushered in the new era of "Protein Engineering". The field of protein engineering has, however, evolved rapidly since then and the last fifteen years have witnessed remarkable advances through the use of new chemical, biochemical and molecular biological tools towards the synthesis and manipulation of proteins. The chapters included in this book reflect the rapid evolution of protein engineering and its many applications in basic research, biotechnology, material sciences and therapy. This book will provide the reader with an introduction to state-of the-art concepts and methods and will be of use to anyone interested in the study of proteins, in academia as well as in industry.
Editors and Affiliations
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Department of Biology, Massachusetts Institute of Technology, Cambridge, USA
Caroline Köhrer, Uttam L. RajBhandary
Bibliographic Information
Book Title: Protein Engineering
Editors: Caroline Köhrer, Uttam L. RajBhandary
Series Title: Nucleic Acids and Molecular Biology
DOI: https://doi.org/10.1007/978-3-540-70941-1
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag Berlin Heidelberg 2009
Hardcover ISBN: 978-3-540-70937-4Published: 28 November 2008
Softcover ISBN: 978-3-642-08992-3Published: 25 November 2010
eBook ISBN: 978-3-540-70941-1Published: 07 January 2009
Series ISSN: 0933-1891
Series E-ISSN: 1869-2486
Edition Number: 1
Number of Pages: XI, 347
Topics: Cell Biology, Biochemistry, general, Biochemical Engineering, Biological and Medical Physics, Biophysics, Materials Science, general