Editors:
- Includes supplementary material: sn.pub/extras
Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 332)
Buy it now
Buying options
Tax calculation will be finalised at checkout
Other ways to access
This is a preview of subscription content, log in via an institution to check for access.
Table of contents (6 chapters)
-
Front Matter
-
Back Matter
About this book
In recent years, plants have been increasingly explored for production of biomedicines and vaccine components. The two main advantages of plant systems are low cost and a greater potential for scalability as compared to microbial or animal systems. An additional advantage from the public health point of view is high safety compared to animal systems, which is important for vaccine production: there are no known plant pathogens capable of replicating in animals, and in humans in particular. A particular antigen or a protein has to be expressed in a plant using one of many available platforms; this antigen/protein subsequently needs to be purified or processed, and later formulated into a vaccine or a therapeutic; these need to be delivered to a human or animal body via an appropriate route. Naturally, all these vaccines and therapeutics must be subjected to regulatory approvals prior to their use. Thus, the challenge is to adapt plant-based platforms for production of cost-efficient biomedicals that can be approved by FDA for use as vaccine components or therapeutics which will be competitive against existing vaccines and drugs.
This volume attempts to address the entire spectrum of challenges facing the nascent field of plant-based biomedicals, from the selection of an appropriate production platform to specific methods of downstream processing and regulatory approval issues.
Editors and Affiliations
-
Department of Plant, Soil & Entomological Sciences, University of Idaho, Moscow, USA
Alexander V. Karasev
Bibliographic Information
Book Title: Plant-produced Microbial Vaccines
Editors: Alexander V. Karasev
Series Title: Current Topics in Microbiology and Immunology
DOI: https://doi.org/10.1007/978-3-540-70868-1
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2009
Hardcover ISBN: 978-3-540-70857-5Published: 19 May 2009
Softcover ISBN: 978-3-642-08983-1Published: 19 October 2010
eBook ISBN: 978-3-540-70868-1Published: 29 April 2009
Series ISSN: 0070-217X
Series E-ISSN: 2196-9965
Edition Number: 1
Number of Pages: X, 120
Number of Illustrations: 16 b/w illustrations, 10 illustrations in colour
Topics: Pharmacology/Toxicology, Virology, Medical Microbiology