Skip to main content
SpringerLink
Log in
Book cover

Biotransformations

  • Book
  • © 1999

Overview

Editors:
  1. Kurt Faber

    1. Institute of Organic Chemistry, University of Graz, Graz, Austria

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Very affordable price
  • For the personal libraries of graduates and scientists working at the cutting edge of academic, industrial and pharmaceutical research
  • Includes supplementary material: sn.pub/extras

Part of the book series: Springer Desktop Editions in Chemistry (4143)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (8 chapters)

  1. Front Matter

    Pages I-IX
    Download chapter PDF

  2. Biocatalytic Asymmetric Decarboxylation

    • Hiromichi Ohta
    Pages 1-30

  3. Biocatalytic Applications of Hydroxynitrile Lyases

    • Dean V. Johnson, Herfried Griengl
    Pages 31-55

  4. Stereoinversions Using Microbial Redox-Reactions

    • Andrew J. Carnell
    Pages 57-72

  5. Biotransformations with Peroxidases

    • Waldemar Adam, Michael Lazarus, Chantu R. Saha-Möller, Oliver Weichold, Ute Hoch, Dietmar Häring et al.
    Pages 73-108

  6. Production of Chiral C3- and C4-Units by Microbial Enzymes

    • Sakayu Shimizu, Michihiko Kataoka
    Pages 109-123

  7. Polyamino Acids as Man-Made Catalysts

    • Joanne V. Allen, Stanley M. Roberts, Natalie M. Williamson
    Pages 125-144

  8. Epoxide Hydrolases and Their Synthetic Applications

    • Romano V. A. Orru, Alain Archelas, Roland Furstoss, Kurt Faber
    Pages 145-167

  9. Microbial Models for Drug Metabolism

    • R. Azerad
    Pages 169-218

  10. Back Matter

    Pages 219-229
    Download chapter PDF
Back to top

Keywords

About this book

The use of enzymes – employed either as isolated enzymes, crude protein extracts or whole cells – for the transformation of non-natural organic c- pounds is not an invention of the twentieth century: they have been used for more than one hundred years. However,the object of most of the early research was totally different from that of the present day. Whereas the elucidation of biochemical pathways and enzyme mechanisms was the main driving force for the early studies,in contrast it was mainly during the 1980s that the enormous potential of applying natural catalysts to transform non-natural organic c- pounds was recognized. This trend was particularly well enhanced by the recommendation of the FDA-guidelines (1992) with respect to the use of chiral bioactive agents in enantiopure form. During the last two decades, it has been shown that the substrate tolerance of numerous biocatalysts is often much wider than previously believed. Of course,there are many enzymes which are very strictly bound to their natural substrate(s). They play an important role in metabolism and they are gener- ly not applicable for biotransformations. On the other hand, an impressive number of biocatalysts have been shown to possess a wide substrate tolerance by keeping their exquisite catalytic properties with respect to chemo-, reg- and, most important, enantio-selectivity. This made them into the key tools for biotransformations.

Editors and Affiliations

  • Institute of Organic Chemistry, University of Graz, Graz, Austria

    Kurt Faber

Bibliographic Information

  • Book Title: Biotransformations

  • Editors: Kurt Faber

  • Series Title: Springer Desktop Editions in Chemistry

  • DOI: https://doi.org/10.1007/3-540-69791-8

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1999

  • Hardcover ISBN: 978-3-540-64496-5Due: 20 October 1998

  • Softcover ISBN: 978-3-540-66949-4Published: 14 February 2000

  • eBook ISBN: 978-3-540-69791-6Published: 30 June 2003

  • Edition Number: 1

  • Number of Pages: VIII, 224

  • Number of Illustrations: 33 b/w illustrations

  • Additional Information: Originally published as volume 63 in the series: Advances in Biochemical Engineering / Biotechnology

  • Topics: Organic Chemistry, Biotechnology, Biochemistry, general

Publish with us

Policies and ethics

Back to top

Search

Navigation