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  • Book
  • © 2007

Molecular Microbiology of Heavy Metals

  • Tracks recent progress in understanding metal-microbe interactions
  • Presents a molecular systems theoretical approach as well as results that may lead to the level of real mechanistic understanding
  • With contributions written by internationally renowned scientists
  • Includes supplementary material: sn.pub/extras

Part of the book series: Microbiology Monographs (MICROMONO, volume 6)

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Table of contents (17 chapters)

  1. Front Matter

    Pages I-VIII
  2. Molecular Physiology of Metal-Microbe Interactions According to Mechanisms

    1. Front Matter

      Pages 1-2
    2. Understanding How Cells Allocate Metals

      • Stephen Tottey, Duncan R. Harvie, Nigel J. Robinson
      Pages 3-35
    3. Metalloregulators: Arbiters of Metal Sufficiency

      • John D. Helmann, Sumarin Soonsanga, Scott Gabriel
      Pages 37-71
    4. Transcriptomic Responses of Bacterial Cells to Sublethal Metal Ion Stress

      • Jon L. Hobman, Kaneyoshi Yamamoto, Taku Oshima
      Pages 73-115
    5. Bacterial Transition Metal Homeostasis

      • Dietrich H. Nies
      Pages 117-142
    6. Biosensing of Heavy Metals

      • Hauke Harms
      Pages 143-157
    7. A Glossary of Microanalytical Tools to Assess the Metallome

      • Dirk Wesenberg, Corinna Bleuel, Gerd-Joachim Krauss
      Pages 159-186
  3. Molecular Physiology of Metal-Microbe Interactions According to Groups

    1. Front Matter

      Pages 187-188
    2. Acquisition of Iron by Bacteria

      • Volkmar Braun, Klaus Hantke
      Pages 189-219
    3. New Transport Deals for Old Iron

      • Gregor Grass
      Pages 221-233
    4. Manganese: Uptake, Biological Function, and Role in Virulence

      • Krisztina M. Papp-Wallace, Andrea S. Moomaw, Michael E. Maguire
      Pages 235-257
    5. How Bacteria Handle Copper

      • David Magnani, Marc Solioz
      Pages 259-285
    6. Microbial Physiology of Nickel and Cobalt

      • Robert P. Hausinger, Deborah B. Zamble
      Pages 287-320
    7. Zinc, Cadmium, and Lead Resistance and Homeostasis

      • Christopher Rensing, Bharati Mitra
      Pages 321-341
    8. Microbiology of the Toxic Noble Metal Silver

      • Sylvia Franke
      Pages 343-355
    9. Arsenic Metabolism in Prokaryotic and Eukaryotic Microbes

      • Hiranmoy Bhattacharjee, Barry P. Rosen
      Pages 371-406
    10. Reduction and Efflux of Chromate by Bacteria

      • Carlos Cervantes, Jesús Campos-García
      Pages 407-419
    11. Molybdate and Tungstate: Uptake, Homeostasis, Cofactors, and Enzymes

      • Guenter Schwarz, Peter-Leon Hagedoorn, Katrin Fischer
      Pages 421-451

About this book

All forms of life depend on a variety of heavy metal ions. Nearly one-third of all gene products require a metal ion for proper folding or function. However, even metals generally regarded as non-poisonous are toxic at higher concentrations, including the essential ones. Thus, sensitive regulation of metal uptake, storage, allocation and detoxification is needed to maintain cellular homeostasis of heavy metal ions.

Molecular Microbiology of Heavy Metals includes chapters on allocation of metals in cells, metal transporter, storage and metalloregulatory proteins, cellular responses to metal ion stress, transcription of genes involved in metal ion homeostasis, uptake of essential metals, metal efflux and other detoxification mechanisms. Also discussed are metal bioreporters for the nanomolar range of concentration and tools to address the metallome. Chapters in the second part cover specific metals such as Fe, Mn, Cu, Ni, Co, Zn and Mo as key nutrient elements and Ag, As, Cd, Hg and Cr as toxic elements.

Bibliographic Information

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access