Overview
- First book on a very hot topic: the phenomenon of asymmetry in cell division in plants and animals
- Includes supplementary material: sn.pub/extras
Part of the book series: Progress in Molecular and Subcellular Biology (PMSB, volume 45)
Access this book
Tax calculation will be finalised at checkout
Other ways to access
Table of contents (10 chapters)
-
Front Matter
-
Back Matter
Keywords
About this book
Cell biologists have recently become aware that the asymmetry of cell division is an important regulatory phenomenon in the fate of a cell. During development, cell diversity originates through asymmetry; in the adult organism asymmetric divisions regulate the stem cell reservoir and are a source of the drift that contributes to the aging of organisms with renewable cell compartments. Because of the concept of semi-conservative DNA synthesis, it was thought that the distribution of DNA between daughter cells was symmetric. The analysis of the phenomenon in cells during mitosis, however, revealed the asymmetry in the distribution of the genetic material that creates the drift contributing to aging of mammals. On the other hand, cancer cells can originate from a deregulation of asymmetry during mitosis in particular during stem cell expansion. The book describes the phenomenon in different organisms from plants to animals and addresses its implications for the development of the organism, cell differentiation, human aging and the biology of cancers.
Reviews
From the reviews:
"Asymmetric cell division is a process whereby one cell generates two daughter cells that differ in size or developmental potential . … The book is targeted at scientists working in the field … . it would be appropriate for a biology department’s library. … Scientists or students, however, who work in this field and who have already read some of the mainstream review articles, might find this book a useful addition for understanding the less well-covered areas of asymmetric cell division research." (Juergen Knoblich, Development, Vol. 134 (24), 2007)
Editors and Affiliations
Bibliographic Information
Book Title: Asymmetric Cell Division
Editors: Alvaro Macieira-Coelho
Series Title: Progress in Molecular and Subcellular Biology
DOI: https://doi.org/10.1007/978-3-540-69161-7
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag Berlin Heidelberg 2007
Hardcover ISBN: 978-3-540-69160-0Published: 03 April 2007
Softcover ISBN: 978-3-642-08865-0Published: 22 November 2010
eBook ISBN: 978-3-540-69161-7Published: 21 April 2007
Series ISSN: 0079-6484
Series E-ISSN: 2197-8484
Edition Number: 1
Number of Pages: XII, 248
Topics: Developmental Biology, Cell Biology, Cancer Research