ACNE and ROSACEA

1. Front Matter

   Pages I-XIV

   PDF

2. History of Acne and Rosacea

   1. History of Acne and Rosacea

      • Gerd Plewig, Albert M. Kligman

      Pages 1-23

3. Acne

   1. Etiology, Pathophysiology, and Nosology of Acne

      1. Prevalence

         • Gerd Plewig, Albert M. Kligman

         Pages 27-27

      2. A Précis of Pathogenesis

         • Gerd Plewig, Albert M. Kligman

         Pages 28-29

      3. Anatomy of Follicles

         • Gerd Plewig, Albert M. Kligman

         Pages 30-49

      4. Epidermal Lipids

         • Gerd Plewig, Albert M. Kligman

         Pages 50-55

      5. Sebaceous Glands

         • Gerd Plewig, Albert M. Kligman

         Pages 57-81

      6. Micro-organisms

         • Gerd Plewig, Albert M. Kligman

         Pages 83-95

      7. Endocrinology of Acne

         • Gerd Plewig, Albert M. Kligman

         Pages 96-98

      8. The Evolution of the Comedo

         • Gerd Plewig, Albert M. Kligman

         Pages 99-101

      9. Dynamics of Primary Comedo Formation

         • Gerd Plewig, Albert M. Kligman

         Pages 103-109

      10. Dynamics of Secondary Comedo Formation

          • Gerd Plewig, Albert M. Kligman

          Pages 111-145

      11. Dynamics of Inflammation

          • Gerd Plewig, Albert M. Kligman

          Pages 146-148

      12. Inflammatory Lesions and Sequels

          • Gerd Plewig, Albert M. Kligman

          Pages 149-193

      13. Scope of Scars

          • Gerd Plewig, Albert M. Kligman

          Pages 194-243

      14. Classification of Acne

          • Gerd Plewig, Albert M. Kligman

          Pages 245-249

   2. Models of Acne

      1. Acne in Animals: Canine and Feline Acne

         • Gerd Plewig, Albert M. Kligman

         Pages 253-253

      2. Animal Models

         • Gerd Plewig, Albert M. Kligman

         Pages 254-267

      3. Human Sebocyte Culture

         • Gerd Plewig, Albert M. Kligman

         Pages 268-268

   3. The Acne

      1. Acne in Childhood

         • Gerd Plewig, Albert M. Kligman

         Pages 271-279

Twenty-five years have elapsed since the first publication of this book. The growth of basic knowledge since then has been both enormous and momentous. This has been a joyous enterprise for us. Our ability to treat acne and rosacea ef­ fectively has outpaced the vastly expanded understanding of their etiologies. Acne today is not only an eminently treatable disease; in some cases, for exam­ is actually curable. We think that no case is so severe as to pIe acne conglobata, it be beyond help with the array of diverse drugs now available. Treatment failure is really physician failure. Prevention of acne in high-risk children has also be­ come a promising possibility, now that it is possible to identify small comedones in prepuberty, as early as the age of 7 years. Topical comedolytic agents such as retinoids prescribed at the incipient stage might then prevent the evolution of the full-fledged disorder. This therapeutic maneuver could prevent the dreaded sequel of scarring. We adhere firmly to the beliefs expressed in 1975 regarding our mission. This text is dedicated to the dermatologists and other practitioners who must diagnose and treat these disfiguring, remarkably protean, common disorders.

• Dermatitis
• Rosacea
• anatomy
• child
• childhood
• diagnosis
• endocrinology
• histopathology
• inflammation
• pathophysiology
• physiology
• stress
• therapy
• treatment

• Klinik und Poliklinik für Dermatologie und Allergologie Klinikum München, Ludwig-Maximilians-Universität München, München, Germany

  Gerd Plewig

• Department of Dermatology, University of Pennsylvania, Philadelphia, USA

  Albert M. Kligman

Policies and ethics