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Biosynthesis

Aromatic Polyketides, Isoprenoids, Alkaloids

  • Book
  • © 2000

Overview

Editors:
  1. Finian J. Leeper

    1. Department of Chemistry, University of Cambridge, Cambridge, Great Britain

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    You can also search for this editor in PubMed   Google Scholar

  2. John C. Vederas

    1. Department of Chemistry, University of Alberta, Edmonton, Canada

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    You can also search for this editor in PubMed   Google Scholar

  • This series presents critical reviews of the present position and future trends in modern chemical research
  • Short and concise reports on chemistry, each written by the world's renowned experts
  • Still valid and useful after 5 or 10 years

Part of the book series: Topics in Current Chemistry (TOPCURRCHEM, volume 209)

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Table of contents (5 chapters)

  1. Front Matter

    Pages I-X
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  2. Biosynthesis of Aromatic Polyketides

    • Ben Shen
    Pages 1-51

  3. Cyclization Enzymes in the Biosynthesis of Monoterpenes, Sesquiterpenes, and Diterpenes

    • Edward M. Davis, Rodney Croteau
    Pages 53-95

  4. Biosynthesis of Prenylated Alkaloids Derived from Tryptophan

    • Robert M. Williams, Emily M. Stocking, Juan F. Sanz-Cervera
    Pages 97-173

  5. Tropane and Related Alkaloids

    • Thomas Hemscheidt
    Pages 175-206

  6. Biosynthesis and Metabolism of Pyrrolizidine Alkaloids in Plants and Specialized Insect Herbivores

    • Thomas Hartmann, Dietrich Ober
    Pages 207-243

  7. Back Matter

    Pages 245-247
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Keywords

About this book

This book is the second of two volumes that deal with discovery of chemical pathways of biosynthesis of natural products (secondary metabolites). The first volume covered the use of isotopes in biosynthetic research and the formation of enzyme cofactors and reduced polyketides. This second volume describes biosynthesis of aromatic (unreduced) polyketides, enzymes responsible for cyclization of terpenoids (isoprenoids), and biochemical generation of selected classes of alkaloids (prenylated tryptophan, tropane, pyrrolizidine). Knowledge of the pathways and the techniques to elucidate them opens the door to combinatorial biosynthesis as well as to the production of targeted pharmaceutical agents utilizing a combination of chemistry, molecular biology and protein biochemistry.

Editors and Affiliations

  • Department of Chemistry, University of Cambridge, Cambridge, Great Britain

    Finian J. Leeper

  • Department of Chemistry, University of Alberta, Edmonton, Canada

    John C. Vederas

Bibliographic Information

  • Book Title: Biosynthesis

  • Book Subtitle: Aromatic Polyketides, Isoprenoids, Alkaloids

  • Editors: Finian J. Leeper, John C. Vederas

  • Series Title: Topics in Current Chemistry

  • DOI: https://doi.org/10.1007/3-540-48146-X

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2000

  • Hardcover ISBN: 978-3-540-66573-1Published: 27 March 2000

  • Softcover ISBN: 978-3-642-08583-3Published: 06 December 2010

  • eBook ISBN: 978-3-540-48146-1Published: 01 July 2003

  • Series ISSN: 0340-1022

  • Series E-ISSN: 1436-5049

  • Edition Number: 1

  • Number of Pages: X, 247

  • Topics: Biochemical Engineering, Organic Chemistry, Biochemistry, general

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