Progress in Diagnostics and Therapy of Prostatic Cancer

1. Front Matter

   Pages I-X

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2. Introduction and New Aspects of the Biology of Prostate Carcinoma

   • H. Huland

   Pages 1-3

3. Value of Digital Rectal Examination, Determination of Prostate-Specific Antigen Concentration and the Use of Transrectal Ultrasonography

   • P. Hammerer, H. Huland

   Pages 5-23

4. Screening for Early Prostate Cancer

   • R. S. Kirby

   Pages 25-30

5. Carcinoma of the Prostate: Science and Treatment

   • J. Waxman

   Pages 31-35

6. Neoadjuvant Androgen Deprivation Before Radical Prostatectomy for Stage T3 Cancer

   • U. W. Tunn, O. Acar, A. J. W. Goldschmidt, The Offenbach Oncological Urology Working Group (A.O.U. E.V.)

   Pages 37-45

7. Partial Versus Complete Androgen Deprivation

   • J. E. Altwein

   Pages 47-52

8. Monthly Microcapsule Depot Form of Leuprorelin: Animal Studies and Internal Structure of Microcapsules

   • Y. Ogawa

   Pages 53-60

9. A Clinical Study Investigating Overall Patient Acceptability of Leuprorelin Acetate for the Treatment of Advanced Prostatic Cancer

   • J. Hetherington, H. Townsend

   Pages 61-67

10. Efficacy of Leuprorelin Acetate Depot in the Treatment of Prostatic Cancer: Results of a Long-Term Follow-Up Study

    • M. Wiesel, E. Kienle, G. Lübben, The German Leuprorelin Study Group

    Pages 69-79

There is now increasing awareness by the general public in European countries that prostate cancer is a serious threat to health, and this has created higher expectations for improved and more effective methods for detecting and treating the disease. However, urologists are very conscious of the limitations of the diagnostic methods that are available and are even more concerned about the apparent lack of therapeutic advances made during the past 50 years since Huggins discovered the fundamental principles of endocrine treatment for is theo­ prostate cancer. Recent efforts to detect the disease when it retically "curable" have been successful, certainly in the USA, but this has highlighted our uncertainty about the best treatment for early stage prostate cancer, and there is no doubt that radical pro­ statectomy is sometimes carried out on men who may not be threa­ tened by their illness. While it is generally accepted that many men with prostate cancer will die of old age rather than this malignancy, it cannot be ignored that this disease kills many others in a process that is frequently lingering, miserable, and humiliating, not only for the victim but also his family. There are many important issues about prostate cancer that remain unclear at the present time, some of which are addressed by the reviews in this book. The debate about early detection and screening can arouse considerable heat in otherwise placid urological mee­ tings.

• Antidrogenbehandlung
• Onkologie
• Sonographie, transreaktale
• Urologie
• Urology
• antiandrogen
• biopsy
• carcinoma
• diagnostics
• oncology
• transrectal
• treatment
• ultrasound

• Royal Gwent Hospital, Newport, Gwent, Great Britain

  W. B. Peeling

• Abteilung für Urologie, Marienkrankenhaus, Universität Hamburg, Akademisches Lehrkrankenhaus, Hamburg, Germany

  Hermann Becker

Policies and ethics