Immunology and Its Impact on Infections in Surgery

1. Front Matter

   Pages I-XXVII

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2. Animal Models

   1. Front Matter

      Pages 1-1

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   2. Yersinia enterocolitica Infection in Mice: A Possible Experimental Model for the Immunobiology of Gram-Negative Infections

      • I. B. Autenrieth, M. Beer, P. Hantschmann, E. Bohn, J. Heesemann

      Pages 3-7

   3. Development of a New Animal Model for Chronic Abscess-Forming Peritonitis

      • W.-G. Steinmetz, J. Schneider, H. W. Volk

      Pages 8-11

   4. Tolerance to Endotoxin in an Animal Model of Acute Pancreatitis Is Associated with Improved Cellular Immune Function

      • P. J. Curley, R. G. Holzheimer, M. Nestor, I. Saporoschetz, J. A. Mannick, M. L. Rodrick

      Pages 12-19

   5. Prolonged and Recurrent Endotoxemia in Domestic Pigs: A First Step Toward a Porcine Model of Human Multiple Organ Failure?

      • B. Klosterhalfen, S. Hauptmann, C. J. Kirkpatrick

      Pages 20-26

   6. Endotoxin, Interferon-γ, Biopterin, Serum Phospholipase A₂ Activity and β-Endorphin as Differentiation Factors and Their Correlations in the Acute Immune Response During Lethal Gram-Negative Sepsis in LEW Rats

      • A. Hunsicker, W. Kullich, W. Weissenhofer, D. Lorenz, J. Petermann, K. Boden et al.

      Pages 27-35

3. Gene Expression

   1. Front Matter

      Pages 37-37

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   2. The Effects of Burn Injury on Cytokine Production and Gene Expression

      • A. F. Horgan, J. A. Mannick, D. S. O’Riordan, M. V. Mendez, R. C. Holzheimer, K. Collins et al.

      Pages 39-53

   3. Genomic Fingerprinting for the Evaluation of Epidemic Processes

      • A. Schwarzkopf, H. Böhm, H. Schmidt, J. Heesemann, H. Karch

      Pages 54-60

   4. Interleukin-2 Receptor Expression Is Unaffected by Thermal Injury

      • D. S. O’Riordain, R. G. Holzheimer, M. Mendez, K. Collins, J. A. Mannick, M. L. Rodrick

      Pages 61-64

   5. Keratinocytes Express an Intracellular Marker Gene and Regenerate the Epidermis in Porcine Full-Thickness Wounds After Retroviral Gene Transfer

      • P. Vogt, D. Hatzis, S. Thompson, R. Mulligan, C. Andree, E. Eriksson

      Pages 65-67

   6. The Influence of Non-specific Inflammatory and Immunological Reactions on the Expression of Major Histocompatibility Complex and Activation Antigens After Murine Hepatic Transplantation

      • H.-J. Gassel, R. Engemann, W. Timmermann, A. M. Gassel, A. Thiede

      Pages 68-75

4. Cellular Activation (1)

   1. Front Matter

      Pages 77-77

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   2. Cellular Endothelial Interaction and the Activation of Plasma Cascade Systems in Sepsis

      • A. O. Aasen, L. Buø

      Pages 79-83

   3. The Role of the Macrophage in Early Post-traumatic Immunosuppression

      • C. C. Baker

      Pages 84-90

   4. Role and Measurement of Endotoxin in Septic Shock

      • R. Urbaschek, K.-P. Becker, R. S. McCuskey, B. Urbaschek

      Pages 91-95

   5. Normal Human Immune Peritoneal Cells: Predominance of Memory Lymphocytes

      • U. Kubicka, W. L. Olszewski, W. Tarnowski, K. Bielecki, A. Ziolkowska

      Pages 96-104

   6. Supplementation of Postoperative Enteral Nutrition with Arginine, RNA, and Omega-3 Fatty Acids Increases the Activity of Blood Monocytes in Cancer Patients

      • M. Senkal, M. Kemen, H.-H. Homann, T. Harings, J. Baier, V. Zumtobel

      Pages 105-109

   7. Mild Surgery-Induced Changes in Human Peripheral Blood Lymphocytes

      • E. Bresciano, D. Mancino, M. L. Vuotto, P. Gazzerro, M. T. Ielpo, V. Mazzoccoli et al.

      Pages 110-113

In this book, the recent developments in immunology and the impact on the treatment of infections in critical care and in surgery are presented, also describing how cellular immunology influences clinical treatment. This information helps in understanding the pathogenesis of infections in surgery and critical care. The impact of a standard treatment such as antibiotic therapy is evaluated and possible future therapy modalities outlined. This book will be of interest to clinicians and immunologists as scientists of both specialties have contributed to the book.

• Antigen
• Hepatitis
• Interferon
• Sepsis
• Surgery
• Transplantation
• antibiotics
• gram-negative infection
• infection
• infections

• Chirurgische Universitäts- und Poliklinik, Universität Würzburg, Würzburg, Germany

  Rainer Engemann, Rene Holzheimer, A. Thiede

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