Proteolytic Enzymes and Wound Healing

1. Front Matter

   Pages I-VII

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2. Pathobiology of Necrosis

   • P. K. Das, W. Westerhof

   Pages 1-6

3. Types of Chronic Wounds: Indications for Enzymatic Débridement

   • R. D. Sinclair, T. J. Ryan

   Pages 7-21

4. Why Wounds Need to Be Débrided

   • H. P. Ehrlich

   Pages 23-29

5. Surgical Versus Enzymatic Débridement

   • L. Donati, E. Magliano, M. Colonna, S. Garbin

   Pages 31-48

6. Evaluation of Wound Débridement Using Computerized Image Analysis

   • J. R. Mekkes, W. Westerhof, E. van Riet Paap, J. Habraken, O. Estevez

   Pages 49-58

7. Types of Enzymes on the Market

   • W. Vanscheidt, J. M. Weiss

   Pages 59-73

8. The Role of Collagenase in Wound Healing

   • R. A. Hatz, N. C. S. von Jan, F. W. Schildberg

   Pages 75-88

9. Collagenase, Aid for Treatment of Decubitus Ulcers

   • M. W. F. van Leen

   Pages 89-97

10. Future Prospects of Proteolytic Enzymes and Wound Healing

    • W. Westerhof

    Pages 99-102

11. Back Matter

    Pages 103-106

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This book is the fruit of lectures given during the symposium "Proteolytic Enzymes and Wound Healing" at the Joint Meet­ ing of the Wound Healing Society and the European Tissue Repair Society held in Amsterdam, August 22-25, 1993. Look­ ing back, we can conclude with satisfaction that the meeting was a great success, with regard to both the number of partici­ pants and the scientific level. Enormous progress is being made in the field of wound heal­ ing and tissue repair. It was therefore of prime importance that one fundamental aspect in the healing of chronic wound- the proteolytic debridement of tissue necrosis - be given thorough attention during the above-mentioned symposium. Renowned authors dealt with the various aspects of proteoly­ tic enzymes and wound healing, so that a unique overview was given. The lectures were written up and arranged into the various chapters of this book, which should provide the reader with a practical guide in understanding and treating necrotic wounds. Wiete Westerhof, M. D., Ph. D. President of the Organizing Committee of the Joint Meeting of the Wound Healing Society and the European Tissue Repair Society Contents Pathobiology of Necrosis P. K. Das and W. Westerhof.. ................................... .

• attention
• biology
• decubitus ulcer
• enzymes
• evaluation
• image analysis
• joint
• necrosis
• pathobiology
• tissue
• treatment

• Academic Medical Center, Department of Dermatology, University of Amsterdam, Amsterdam, The Netherlands

  W. Westerhof

• Universitäts-Hautklinik, Freiburg i. Br., Germany

  W. Vanscheidt

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