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Shock, Sepsis, and Organ Failure

Second Wiggers Bernard Conference May 27–30, 1990, Schloß Dürnstein, Austria

  • Conference proceedings
  • © 1991

Overview

Editors:
  1. Günther Schlag

    1. Ludwig-Boltzmann-Institut für experimentelle und klinische Traumatologie, Wien, Austria

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  2. Heinz Redl

    1. Ludwig-Boltzmann-Institut für experimentelle und klinische Traumatologie, Wien, Austria

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  3. John H. Siegel

    1. Maryland Institute for Emergency Medical Services Systems, Department of Surgery, Medical School, University of Maryland, Baltimore, USA
      School of Medicine, John Hopkins University, Baltimore, USA

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  4. Daniel L. Traber

    1. Shriners Burns Institute and The University of Texas Medical Branch, Galveston, USA

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Table of contents (17 papers)

  1. Front Matter

    Pages I-X
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  2. Gut as a Source of Organ Failure

    1. Front Matter

      Pages 1-1
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    2. Hypoxic Damage of the Gut in Shock

      • U. Haglund
      Pages 3-22

    3. Experimental Evidence of Bacterial Translocation in Trauma

      • Edwin A. Deitch
      Pages 23-52

    4. Bacterial Translocation in a Baboon Model of Hypovolemic-Traumatic Shock

      • G. Schlag, H. Redl, H. P. Dinges, J. Davies, K. Radmore
      Pages 53-90

    5. Bacterial Translocation Across a Histologically Intact Intestinal Mucosa

      • C. L. Wells, S. L. Erlandsen, D. L. Dunn, R. L. Simmons
      Pages 91-117

    6. Clinical Evidence of Bacterial Translocation from the Gut

      • B. F. Rush Jr., J. N. McCullough
      Pages 118-132

    7. Role of Bacterial Translocation and Selective Gut Decontamination in the Development of Multiple Organ Failure

      • R. J. A. Goris, I. P. T. van Bebber, Th. Hendriks
      Pages 133-146

  3. Metabolic Aspects of the Liver in Sepsis

    1. Front Matter

      Pages 147-147
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    2. The Liver as Modulator of the Host-Defense Response: Host-Defense Failure Disease as a Manifestation of Hepatic Decompensation

      • John H. Siegel
      Pages 149-206

    3. Concepts of Liver Protein Metabolism in Sepsis

      • P. O. Hasselgren, D. von Allmen, J. E. Fischer
      Pages 207-234

    4. Increased Glucose Uptake and Superoxide Anion Production after Priming or Activation of Hepatic Phagocytes: A Potential Source of Liver Damage

      • John J. Spitzer, Zoltan Spolarics, Abraham P. Bautista, Károly Mészáros, Agnes Schuler, Charles H. Lang
      Pages 235-254

    5. Modulation of Hepatic Function in Endotoxemia by Intercellular Communication

      • J. A. Spitzer
      Pages 255-275

  4. Endothelium as a Target in Sepsis

    1. Front Matter

      Pages 277-277
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    2. Cytokine-Dependent Interleukin-8 Expression and its Role in Cell Communication

      • Steven L. Kunkel, Theodore Standiford, Robert M. Strieter
      Pages 279-296

    3. Trauma and Sepsis Induced Activation of Granulocytes, Monocytes/Macrophages and Endothelial Cells in Primates

      • H. Redl, G. Schlag, H. P. Dinges, S. Bahrami, W. A. Buurman, U. Schade et al.
      Pages 297-322

    4. Molecular Mechanisms of Neutrophil-Mediated Pulmonary Microvascular Injury: Role of Adhesion Proteins

      • Asrar B. Malik
      Pages 323-350

    5. Pathogenetic Linkages between Gram Negative Septic Shock and the Cellular Initiation and Regulation of Coagulation

      • Thomas S. Edgington
      Pages 351-369

    6. Sepsis, Disseminated Intravascular Coagulation and Multiorgan Failure: Catastrophic Events in Severe Burns

      • H. A. Linares
      Pages 370-398

    7. Mechanisms of Vascular Impairment During Endotoxaemia with Special Reference to the Role of the L-arginine Pathway

      • I. Fleming, B. L. Furman, G. A. Gray, M. O. Guc, G. Julou-Schaeffer, M. Bigaud et al.
      Pages 399-424
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Keywords

About this book

The Wiggers Bernard Conferences, named after two great physiologists of the past, are an­ nual gatherings of the leaders in the field of shock. The meetings focus on specific areas of which appears to be showing the most advancement during the previous year. There are se­ veral types of sessions; informal presentations during which the seminarian can be intenup­ ted in order to clarify a particular point; formal discussions follow each presentation; these are followed by informal gatherings in which these discussions continue during meals and libation in a very relaxed environment. The 1990 meeting took place in Durnstein, Austria. A small hamlet in the wine growing area of the Wachau valley, on the Danube above Vien­ na. This was the site of a former citadel where the English King Richard the Lion-Heart (Coeur de Uon) was held for ransom during the middle ages. The frank beauty and hospi­ tality of this area in addition to the ancient Roman adage "in vino veritas" acted as a catalyst to crystalize the thoughts of this interdisciplinary group of scientists as they discussed the following areas: 1. Gut as a Source of Organ Failure 2. Metabolic Aspects of the Liver in Sepsis 3. Endothelium as a Target'in Sepsis We would like to thank the participants of the conference for taking time away from their very productive and busy schedules to participate in the conference and for the prompt pre­ sentation of their manuscripts and editions of their discussions.

Editors and Affiliations

  • Ludwig-Boltzmann-Institut für experimentelle und klinische Traumatologie, Wien, Austria

    Günther Schlag, Heinz Redl

  • Maryland Institute for Emergency Medical Services Systems, Department of Surgery, Medical School, University of Maryland, Baltimore, USA

    John H. Siegel

  • School of Medicine, John Hopkins University, Baltimore, USA

    John H. Siegel

  • Shriners Burns Institute and The University of Texas Medical Branch, Galveston, USA

    Daniel L. Traber

Bibliographic Information

  • Book Title: Shock, Sepsis, and Organ Failure

  • Book Subtitle: Second Wiggers Bernard Conference May 27–30, 1990, Schloß Dürnstein, Austria

  • Editors: Günther Schlag, Heinz Redl, John H. Siegel, Daniel L. Traber

  • DOI: https://doi.org/10.1007/978-3-642-76511-7

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1991

  • Softcover ISBN: 978-3-540-53831-8Published: 17 May 1991

  • eBook ISBN: 978-3-642-76511-7Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: X, 457

  • Topics: Emergency Medicine, Internal Medicine, Infectious Diseases

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