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Shock, Sepsis, and Organ Failure

First Wiggers Bernard Conference

  • Conference proceedings
  • © 1990

Overview

Editors:
  1. Günther Schlag

    1. Ludwig-Boltzmann-Institut für experimentelle und klinische Traumatologie, Austria

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  2. Heinz Redl

    1. Ludwig-Boltzmann-Institut für experimentelle und klinische Traumatologie, Austria

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  3. John H. Siegel

    1. Maryland Institute for Emergency Medical Services Systems, University of Maryland, Medical School and John Hopkins University, School of Medicine, Baltimore, USA
      Department of Surgery, University of Maryland, Medical School and John Hopkins University, School of Medicine, Baltimore, USA

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Table of contents (40 papers)

  1. Front Matter

    Pages I-XI
    Download chapter PDF

  2. Carl J. Wiggers, M.D.

    1. Carl J. Wiggers, M.D.

      • Daniel L. Traber
      Pages 1-7

  3. Claude Bernard

    1. Claude Bernard

      • Daniel L. Traber
      Pages 8-11

  4. What is Multi-Organ-Failure Is it a Sequence of Organ Failures or a Systemic Disease?

    1. Front Matter

      Pages 13-13
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    2. Clinical Manifestations and Sequences of Organ Failure

      • Arthur E. Baue
      Pages 15-39

    3. Discussion

      • Günther Schlag, Heinz Redl, John H. Siegel
      Pages 40-43

    4. The Specific Role of Ards in the Development of Multiple Organ Failure

      • H. Benzer, W. Koller, Th. J. Luger, G. Putz, Ch. Putensen, U. Waibel
      Pages 44-60

    5. Discussion

      • Günther Schlag, Heinz Redl, John H. Siegel
      Pages 61-65

    6. Quantification of Organ Failure

      • Michael L. Nerlich
      Pages 66-82

    7. Discussion

      • Günther Schlag, Heinz Redl, John H. Siegel
      Pages 83-91

    8. The Metabolic Basis of the Septic Multiple Organ Failure Syndrome: Abnormal Energetic Fuel Control, Pathophysiologic Proteolysis and Futile Cycling of Hepatically Synthesized Substrates

      • John H. Siegel
      Pages 92-143

    9. Discussion

      • Günther Schlag, Heinz Redl, John H. Siegel
      Pages 144-150

    10. Humoral and Cellular Activation in Blood Leading to Organ Failure

      • Heinz Redl, Günther Schlag
      Pages 151-196

    11. Discussion

      • Günther Schlag, Heinz Redl, John H. Siegel
      Pages 197-209

    12. Endothelium as the Interface between Blood and Organ in the Evolution of Organ Failure

      • Günther Schlag, Heinz Redl
      Pages 210-271

    13. Discussion

      • Günther Schlag, Heinz Redl, John H. Siegel
      Pages 272-277

    14. Cellular Metabolic Responses in Endotoxemia, and a Hypothesis for the Mechanism of Hepatic Failure in Endotoxic Shock

      • John J. Spitzer, Julia Bojta, Charles H. Lang, Károly Mészáros
      Pages 278-294

    15. Discussion

      • Günther Schlag, Heinz Redl, John H. Siegel
      Pages 295-303

  5. Cellular Events in Trauma and Sepsis Suppression Versus Activation or Both?

    1. Front Matter

      Pages 305-305
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    2. Posttraumatic Immune Suppression as Initiator of Organ Failure

      • E. Faist, M. Storck, W. Ertel, A. Mewes
      Pages 307-328
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Keywords

About this book

The First Wiggers Bernard Conference on Shock, Sepsis, and Organ Failure was envisaged as a meeting of American and European Scientists. It was named after two researchers, one from the "Old" and one from the "New World", who are wellknown for their outstanding achievements in shock research and experimental medicine. This meeting was a point of de­ parture for a series of workshops that will focus on two to three main topics dealt with in detail by experts in their respective fields. The First Wiggers Bernard Conference addressed three main questions: 1. Multi-organ-failure - is it a sequence of organ failures or a systemic disease? 2. Cellular events in trauma and sepsis - are they due to suppression, activation or both? 3. Mediators of organ failure - are LPS or sepsis necessary? Although many answers were given in this first session, numerous issues remain to be clarified due to the enormous complexity of the subject. How­ ever, the stage was set for encounters between clinicians and basic medical researchers, since theoretical knowledge will be useful to the clinician ex­ ploring new approaches to diagnosis, prophylaxis, and therapy. The conference could not have been organized without the generous sup­ port of the Immuno Company, Vienna, Austria. May we express our special thanks to Dr. Eibl, managing director and head of the research division of Immuno AG, not only for granting financial support but also for his valuable advice, encouragement, and scientific expertise.

Editors and Affiliations

  • Ludwig-Boltzmann-Institut für experimentelle und klinische Traumatologie, Austria

    Günther Schlag, Heinz Redl

  • Maryland Institute for Emergency Medical Services Systems, University of Maryland, Medical School and John Hopkins University, School of Medicine, Baltimore, USA

    John H. Siegel

  • Department of Surgery, University of Maryland, Medical School and John Hopkins University, School of Medicine, Baltimore, USA

    John H. Siegel

Bibliographic Information

  • Book Title: Shock, Sepsis, and Organ Failure

  • Book Subtitle: First Wiggers Bernard Conference

  • Editors: Günther Schlag, Heinz Redl, John H. Siegel

  • DOI: https://doi.org/10.1007/978-3-642-75644-3

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin, Heidelberg 1990

  • Softcover ISBN: 978-3-540-52495-3Published: 13 August 1990

  • eBook ISBN: 978-3-642-75644-3Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XI, 660

  • Number of Illustrations: 22 b/w illustrations

  • Topics: Internal Medicine, Emergency Medicine

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