Implementation and Redesign of Catalytic Function in Biopolymers

1. Front Matter

   Pages I-IX

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2. Design and Construction of Novel Peptides and Proteins by Tailored Incorporation of Coenzyme Functionality

   • Barbara Imperiali, Kevin A. McDonnell, Michael Shogren-Knaak

   Pages 1-38

3. Functionalization and Properties of Designed Folded Polypeptides

   • Lars Baltzer

   Pages 39-76

4. Incorporation of Noncoded Amino Acids by In Vitro Protein Biosynthesis

   • Marcella A. Gilmore, Lance E. Steward, A. Richard Chamberlin

   Pages 77-99

5. Catalysis Based on Nucleic Acid Structures

   • Michael Famulok, Andreas Jenne

   Pages 101-131

6. Back Matter

   Pages 133-133

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Improvement of the catalytic properties of biological catalysts is equally important in the optimization of industrial processes as in the fundamental understanding of the catalytic machinery at the molecular level. The approaches taken are diverse and span from purely result-oriented, but nevertheless methodologically subtle, making and screening of combinatorial libraries to highly sophisticated tailoring of the environment of active sites. This volume illustrates four different concepts for modifying a given biocatalyst framework or create novel functions using Nature's basic building blocks. Summing up the state-of-the-art biocatalyst engineering it, serves as an orientational landmark and a platform for the specialist and non-expert alike to keep abreast of developments in this rapidly evolving field.

• Amino acid
• Aminoacids
• Aminosäure
• Biocatalysis
• Biokatalyse
• Coenzym
• Protein Engineering
• Proteinengineering

• Institut für Organische Chemie und Biochemie, Technische Universität München, Garching, Germany

  Franz P. Schmidtchen

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