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Mouse Brain Development

  • Book
  • © 2000

Overview

Editors:
  1. André M. Goffinet

    1. Neurobiology Unit, University of Namur Medical School, Namur, Belgium

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  2. Pasko Rakic

    1. Section of Neurobiology, Yale University School of Medicine, New Haven, USA

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    You can also search for this editor in PubMed   Google Scholar

  • This book is the first to focus on brain development in the mouse, which is fast becoming the model of choice for mammalian development studies
  • Includes supplementary material: sn.pub/extras

Part of the book series: Results and Problems in Cell Differentiation (RESULTS, volume 30)

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Table of contents (13 chapters)

  1. Front Matter

    Pages I-XIV
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  2. From Spontaneous to Induced Neurological Mutations: A Personal Witness of the Ascent of the Mouse Model

    • Pasko Rakic
    Pages 1-19

  3. Mapping Genes that Modulate Mouse Brain Development: A Quantitative Genetic Approach

    • Robert W. Williams
    Pages 21-49

  4. Genetic Interactions During Hindbrain Segmentation in the Mouse Embryo

    • Paul A. Trainor, Miguel Manzanares, Robb Krumlauf
    Pages 51-89

  5. Neurogenetic Compartments of the Mouse Diencephalon and some Characteristic Gene Expression Patterns

    • Salvador Martínez, Luis Puelles
    Pages 91-106

  6. Neuronogenesis and the Early Events of Neocortical Histogenesis

    • V. S. Caviness Jr, T. Takahashi, R. S. Nowakowski
    Pages 107-143

  7. Programmed Cell Death in Mouse Brain Development

    • Chia-Yi Kuan, Richard A. Flavell, Pasko Rakic
    Pages 145-162

  8. Neurotrophic Factors: Versatile Signals for Cell-Cell Communication in the Nervous System

    • Carlos F. Ibáñez
    Pages 163-188

  9. Growth Factor Influences on the Production and Migration of Cortical Neurons

    • Janice E. Brunstrom, Alan L. Pearlman
    Pages 189-215

  10. Signalling from Tyrosine Kinases in the Developing Neurons and Glia of the Mammalian Brain

    • Elena Cattaneo, Massimo Gulisano
    Pages 217-240

  11. The Role of the p35/cdk5 Kinase in Cortical Development

    • Young T. Kwon, Li-Huei Tsai
    Pages 241-253

  12. The Reelin-Signaling Pathway and Mouse Cortical Development

    • Isabelle Bar, Catherine Lambert de Rouvroit, André M. Goffinet
    Pages 255-276

  13. The Subpial Granular Layer in the Developing Cerebral Cortex of Rodents

    • Gundela Meyer, Rafael Castro, José Miguel Soria, Alfonso Fairén
    Pages 277-291

  14. Development of Thalamocortical Projections in Normal and Mutant Mice

    • Zoltán Molnár, Anthony J. Hannan
    Pages 293-332

  15. Back Matter

    Pages 333-339
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Keywords

About this book

Our understanding of the molecular mechanisms involved in mammalian brain development remains limited. However, the last few years have wit­ nessed a quantum leap in our knowledge, due to technological improve­ ments, particularly in molecular genetics. Despite this progress, the available body of data remains mostly phenomenological and reveals very little about the grammar that organizes the molecular dictionary to articulate a pheno­ type. Nevertheless, the recent progress in genetics will allow us to contem­ plate, for the first time, the integration of observation into a coherent view of brain development. Clearly, this may be a major challenge for the next century, and arguably is the most important task of contemporary develop­ mental biology. The purpose of the present book is to provide an overview that syn­ thesizes up-to-date information on selected aspects of mouse brain devel­ opment. Given the format, it was not possible to cover all aspects of brain development, and many important subjects are missing. The selected themes are, to a certain extent, subjective and reflect the interests of the contributing authors. Examples of major themes that are not covered are peripheral nervous system development, including myelination, the development of the hippocampus and several other CNS structures, as well as the developmental function of some important morphoregulatory molecules.

Editors and Affiliations

  • Neurobiology Unit, University of Namur Medical School, Namur, Belgium

    André M. Goffinet

  • Section of Neurobiology, Yale University School of Medicine, New Haven, USA

    Pasko Rakic

Bibliographic Information

  • Book Title: Mouse Brain Development

  • Editors: André M. Goffinet, Pasko Rakic

  • Series Title: Results and Problems in Cell Differentiation

  • DOI: https://doi.org/10.1007/978-3-540-48002-0

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2000

  • Softcover ISBN: 978-3-642-53684-7Published: 28 July 2012

  • eBook ISBN: 978-3-540-48002-0Published: 10 August 2012

  • Series ISSN: 0080-1844

  • Series E-ISSN: 1861-0412

  • Edition Number: 1

  • Number of Pages: XIV, 339

  • Number of Illustrations: 136 b/w illustrations

  • Topics: Neurobiology, Developmental Biology, Cell Biology, Biochemistry, general

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