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Acute Promyelitic Leukemia

Molecular Genetics, Mouse Models and Targeted Therapy

  • Book
  • © 2007

Overview

Editors:
  1. Pier Paolo Pandolfi

    1. Memorial Sloan-Kettering Cancer Center, Sloan-Kettering-Institute, New York, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Peter K. Vogt

    1. The Scripps Research Institute, La Jolla, USA

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 313)

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Table of contents (13 chapters)

  1. Front Matter

    Pages I-VII
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  2. APL as a Paradigm in Biomedical Research: A Journey Toward the Cure

    • P. P. Pandolfi
    Pages 1-2

  3. Mouse Models of Acute Promyelocytic Leukemia

    • S. C. Kogan
    Pages 3-29

  4. The PLZF Gene of t(11;17)-Associated APL

    • M. J. McConnell, J. D. Licht
    Pages 31-48

  5. SUMO, the Three Rs and Cancer

    • J. -S. Seeler, O. Bischof, K. Nacerddine, A. Dejean
    Pages 49-71

  6. Emerging Role for MicroRNAs in Acute Promyelocytic Leukemia

    • C. Nervi, F. Fazi, A. Rosa, A. Fatica, I. Bozzoni
    Pages 73-84

  7. The Theory of APL Revisited

    • P. P. Scaglioni, P. P. Pandolfi
    Pages 85-100

  8. Treatment of Acute Promyelocytic Leukemia by Retinoids

    • P. Fenaux, Z. Z. Wang, L. Degos
    Pages 101-128

  9. Arsenic Trioxide and Acute Promyelocytic Leukemia: Clinical and Biological

    • Z. Chen, W. -L. Zhao, Z. -X. Shen, J. -M. Li, S. -J. Chen, J. Zhu et al.
    Pages 129-144

  10. Front Line Clinical Trials and Minimal Residual Disease Monitoring in Acute Promyelocytic Leukemia

    • F. Lo-Coco, E. Ammatuna
    Pages 145-156

  11. Histone Deacetylase Inhibitors in APL and Beyond

    • K. Petrie, N. Prodromou, A. Zelent
    Pages 157-203

  12. Monoclonal Antibody Therapy of APL

    • P. G. Maslak, J. G. Jurcic, D. A. Scheinberg
    Pages 205-219

  13. Targeting APL Fusion Proteins by Peptide Interference

    • A. Melnick
    Pages 221-243

  14. The Design of Selective and Non-selective Combination Therapy for Acute Promyelocytic Leukemia

    • Y. Jing, S. Waxman
    Pages 245-269

  15. Back Matter

    Pages 271-276
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Keywords

About this book

Over the past 10 years, work on acute promyelocytic leukemia (APL) has become the paradigm of translational research that began with the discovery of a recurrent chromosomal translocation, followed by the identification of the genes and proteins involved, finding their molecular functions in transcriptional control, establishing mouse models and culminating in the development  of targeted therapy.

Editors and Affiliations

  • Memorial Sloan-Kettering Cancer Center, Sloan-Kettering-Institute, New York, USA

    Pier Paolo Pandolfi

  • The Scripps Research Institute, La Jolla, USA

    Peter K. Vogt

Bibliographic Information

  • Book Title: Acute Promyelitic Leukemia

  • Book Subtitle: Molecular Genetics, Mouse Models and Targeted Therapy

  • Editors: Pier Paolo Pandolfi, Peter K. Vogt

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-540-34594-7

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2007

  • Hardcover ISBN: 978-3-540-34592-3Published: 13 December 2006

  • eBook ISBN: 978-3-540-34594-7Published: 02 February 2007

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: VIII, 274

  • Number of Illustrations: 7 b/w illustrations, 9 illustrations in colour

  • Topics: Cancer Research

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