Skip to main content
SpringerLink
Log in

Reviews of Physiology, Biochemistry and Pharmacology 156

  • Book
  • © 2006

Overview

Editors:
  1. S.G. Amara

    1. Pittsburgh

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. E. Bamberg

    1. Frankfurt

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  3. S. Grinstein

    1. Toronto

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  4. S.C. Hebert

    1. New Haven

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  5. R. Jahn

    1. Göttingen

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  6. W.J. Lederer

    1. Baltimore

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  7. R. Lill

    1. Marburg

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  8. A. Miyajima

    1. Tokyo

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  9. H. Murer

    1. Zürich

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  10. S. Offermanns

    1. Heidelberg

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  11. G. Schultz

    1. Berlin

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  12. M. Schweiger

    1. Berlin

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Reviews of Physiology, Biochemistry and Pharmacology (REVIEWS, volume 156)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (4 chapters)

  1. Front Matter

    Pages i-iii
    Download chapter PDF

  2. The diverse roles of J-proteins, the obligate Hsp70 co-chaperone

    • E. A. Craig, P. Huang, R. Aron, A. Andrew
    Pages 1-21

  3. Role of the Mediator complex in nuclear hormone receptor signaling

    • M. Belakavadi, J. D. Fondell
    Pages 23-43

  4. An update on acid secretion

    • J. P. Geibel, C. Wagner
    Pages 45-60

  5. Structure–function relationship of the TRP channel superfamily

    • G. Owsianik, D. D'hoedt, T. Voets, B. Nilius
    Pages 61-90
Back to top

Keywords

About this book

Gastric acid plays a primary role in digestion as well as in the sterilization of food and water. Gastric juice contains the most concentrated physiological acid solution (pH~1) as a result + – of H and Cl ion secretion [hydrochloric acid (HCl) production] by parietal cells in the oxyntic mucosa of the stomach. The combined output of the parietal cells leads to the sec- tion of 1–2 l of HCl at a concentration of 150–160 mmol/l into the interior of the stomach. In order to facilitate the production of acid, the parietal cell relies on the generation of a high + concentration of H ions that are transported into the lumen of the gland. This process is fa- + + cilitated by activation of the gastric H ,K -ATPase, which translocates to the apical pole of + – the parietal cell. K as well as ATP hydrolysis and Cl all play critical roles in the activation + + of gastric H ,K -ATPase and are essential for the functioning of the enzyme (Reenstra and Forte 1990). This review will examine the classical proteins that have been linked to acid secretion as well as some recently identi?ed proteins that may modulate gastric acid secretion, in - dition we discuss the known secretagogues, and their receptors including a new receptor, which upon stimulation can lead to acid secretion.

Editors and Affiliations

  • Pittsburgh

    S.G. Amara

  • Frankfurt

    E. Bamberg

  • Toronto

    S. Grinstein

  • New Haven

    S.C. Hebert

  • Göttingen

    R. Jahn

  • Baltimore

    W.J. Lederer

  • Marburg

    R. Lill

  • Tokyo

    A. Miyajima

  • Zürich

    H. Murer

  • Heidelberg

    S. Offermanns

  • Berlin

    G. Schultz, M. Schweiger

Bibliographic Information

  • Book Title: Reviews of Physiology, Biochemistry and Pharmacology 156

  • Editors: S.G. Amara, E. Bamberg, S. Grinstein, S.C. Hebert, R. Jahn, W.J. Lederer, R. Lill, A. Miyajima, H. Murer, S. Offermanns, G. Schultz, … M. Schweiger

  • Series Title: Reviews of Physiology, Biochemistry and Pharmacology

  • DOI: https://doi.org/10.1007/978-3-540-33146-9

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2006

  • Hardcover ISBN: 978-3-540-31123-2Published: 21 February 2006

  • Softcover ISBN: 978-3-642-06824-9Published: 19 October 2010

  • eBook ISBN: 978-3-540-33146-9Published: 23 May 2007

  • Series ISSN: 0303-4240

  • Series E-ISSN: 1617-5786

  • Edition Number: 1

  • Number of Pages: IV, 90

  • Topics: Human Physiology

Publish with us

Policies and ethics

Back to top

Search

Navigation