Overview
- Editors:
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Arnold Eckardstein
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Institute of Clinical Chemistry, University Hospital of Zurich, Zürich, Switzerland
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Table of contents (30 chapters)
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Background
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- P. Cullen, J. Rauterberg, S. Lorkowski
Pages 3-70
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The Impact of Diet
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- M.A. Thijssen, R.P. Mensink
Pages 165-194
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- M. Aviram, M. Kaplan, M. Rosenblat, B. Fuhrman
Pages 263-300
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- H.F.J. Hendriks, A. van Tol
Pages 339-361
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Evidence-Based Anti-Atherosclerotic Drug Therapy
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- R. Paoletti, C. Bolego, A. Cignarella
Pages 365-388
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- R. Robillard, C. Fontaine, G. Chinetti, J.-C. Fruchart, B. Staels
Pages 389-406
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- A. Dendorfer, P. Dominiak, H. Schunkert
Pages 407-442
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- I. Ahrens, C. Bode, K. Peter
Pages 443-462
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Targets of Future Anti-Atherosclerotic Drug Therapy
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- T. Plösch, A. Kosters, A.K. Groen, F. Kuipers
Pages 465-482
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- K.M. Kostner, G.M. Kostner
Pages 519-536
About this book
Cardiovascular diseases continue to be the leading cause of death in the - jority of industrialized countries. The most frequent underlying pathology, namely atherosclerosis, and its clinical sequelae, namely coronary heart d- ease, cerebrovascular disease and peripheral artery disease, remain common although for a long time we have been made aware of avoidable or mo- ?able etiological factors such as smoking, fat-rich diet or lack of exercise, and although these adverse lifestyle factors have been extensively addressed by population-wide primary prevention programs. Cardiovascular morbidity and mortality also remain high despite successful anti-hypertensive and lipid lowering drug therapies which help to reduce cardiovascular morbidity and mortality by about 30% in both secondary and tertiary prevention settings. This can partly be explained by the increasing life expectancy and growing p- portionofelderly people,especiallyinEuropeandNorthAmerica. Inaddition, the World Health Organization makes the alarming prediction that probably in response to the spreading of western dietary behavior and lack of exercise resulting in an increasing prevalence of diabetes, dyslipidemia and hypert- sion, cardiovascular diseases rather than infectious diseases will become the most frequent cause of death worldwide. This volume of the Handbook of Experimental Pharmacology entitled “Atherosclerosis” is divided into four parts and intends to give an overview on the pathogenesis of atherosclerosis, established treatment and prevention regimen, and of perspectives for the development of new treatment modalities.
Editors and Affiliations
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Institute of Clinical Chemistry, University Hospital of Zurich, Zürich, Switzerland
Arnold Eckardstein
